Solid Phase Synthesis of a Functionalized Bis-Peptide Using …
Published 5/15/2012
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In JoVE (1)
Other Publications (6)
- Cadernos De Saúde Pública / Ministério Da Saúde, Fundação Oswaldo Cruz, Escola Nacional De Saúde Pública
- Marine Environmental Research
- Revista Da Associação Médica Brasileira (1992)
- Respiratory Physiology & Neurobiology
- Cadernos De Saúde Pública / Ministério Da Saúde, Fundação Oswaldo Cruz, Escola Nacional De Saúde Pública
- Acta Cirúrgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgia
Articles by Tatiana Teixeira in JoVE
Intravital Imaging of the Mouse Thymus using 2-Photon Microscopy
Laboratory of Immune Regulation, Instituto Gulbenkian de Ciência
We have developed novel laboratory tools and protocols for intravital imaging acquisition of the thymus. Our technique should help in the identification of “niches” within the thymus where T cell development occurs.
Other articles by Tatiana Teixeira on PubMed
[Socio-demographic Factors and the Dengue Fever Epidemic in 2002 in the State of Rio De Janeiro, Brazil]
This study analyzed the dengue fever epidemic in 2002 and the socio-demographic context of the State of Rio de Janeiro, Brazil, using spatial analysis and statistical modeling. The incidence rate was calculated for resident dengue cases in the State in 2002. The study analyzed associations between incidence and socio-demographic variables and spatial autocorrelation using the Moran Global Index, which showed spatial dependence for both the outcome and the independent variables. A multivariate linear regression model was used. The variables' proportion of urban population, percentage of the population with running water, and percentage of coverage by the Family Health Program (FHP) explained 30.2% of the total variance in the epidemic's incidence rate. The model's residuals did not show spatial autocorrelation. The associations were in the expected direction, and the findings are corroborated by other studies that showed higher dengue incidence in areas characterized by growing urbanization and deficient running water and water supply, while highlighting the FHP as an important facilitator of vector control strategies.
Effects of a Nuclear Power Plant Thermal Discharge on Habitat Complexity and Fish Community Structure in Ilha Grande Bay, Brazil
Fish communities and habitat structures were evaluated by underwater visual censuses a rocky location impacted by thermal discharge (I) and at two control locations, one in a Sargassum bed (C1) and the other in a rocky shore with higher structural complexity (C2). Habitat indicators and fish communities exhibited significant differences between the impacted and control locations, with the impacted one showing a significant decrease in fish species richness and diversity, as well as a decrease in benthic cover. At the I location, only 13 fish species were described, and the average water temperature was 32+/-0.4 degrees C, compared with 44 species at C1 (25.9+/-0.3 degrees C) and 33 species at C2 (24.6+/-0.2 degrees C). Significant differences in fish communities among locations were found by ANOSIM with Eucinostomus argenteus, Mugil sp. and Haemulon steindachneri typical of location I, while Abudefduf saxatilis, Stegastes fuscus and Malacoctenus delalandi were typical of the control locations. Our study shows that thermal pollution alters benthic cover and influences fish assemblages by altering composition and decreasing richness.
[Bariatric Surgery: How and Why to Supplement]
Patients who have undergone bariatric surgery are at increased risk of developing nutritional deficiencies from limited food intake and absorption of different nutrients. A systematic review of several database websites (PubMed and ISI Web of Science) was conducted from September 1983 to April 2010 to identify literature related to micronutrient deficiencies occurring after bariatric surgery. Keywords used individually or in various combinations in the search were bariatric surgery, obesity, vitamin/mineral deficiencies, protein deficiency, nutrient absorption and nutrient supplementation. Literature suggests that to prevent or treat nutritional deficiencies resulting from anatomical changes due to surgical techniques nutritional supplementation is usually necessary. The success of oral nutritional supplementation to correct or prevent nutritional deficiencies depends on several factors. Thus, to understand how nutrients can be administered is very important for clinical practice. This review aims to provide help for the best selection of nutrients to ensure an adequate replacement of nutrients in patients who have undergone bariatric surgery.
Impact of Obesity on Airway and Lung Parenchyma Remodeling in Experimental Chronic Allergic Asthma
The impact of obesity on the inflammatory process has been described in asthma, however little is known about the influence of diet-induced obesity on lung remodeling. For this purpose, 56 recently weaned A/J mice were randomly divided into 2 groups. In the C group, mice were fed a standard chow diet, while OB animals received isocaloric high-fat diet to reach 1.5 of the mean body weight of C. After 12 weeks, each group was further randomized to be sensitized and challenged with ovalbumin (OVA) or saline. Twenty-four hours after the last challenge, collagen fiber content in airways and lung parenchyma, the volume proportion of smooth muscle-specific actin in alveolar ducts and terminal bronchiole, and the number of eosinophils in bronchoalveolar lavage fluid were higher in OB-OVA than C-OVA. In conclusion, diet-induced obesity enhanced lung remodeling resulting in higher airway responsiveness in the present experimental chronic allergic asthma.
Spatial Modeling of Dengue and Socio-environmental Indicators in the City of Rio De Janeiro, Brazil
This study analyzed the spatial distribution of dengue in Rio de Janeiro, Brazil, in 2006, and associations between the incidence per 100,000 inhabitants and socio-environmental variables. The study analyzed reported dengue cases among the city's inhabitants, rainfall, Breteau index (for Aedes aegypti and Aedes albopictus), Gini index, and social development index. We conducted mapping and used the global Moran index to measure the indicators' spatial autocorrelation, which was positive for all variables. The generalized linear model showed a direct association between dengue incidence and rainfall, one-month rainfall time lag, Gini index, and Breteau index for A. albopictus. The conditional autoregressive model (CAR) showed a direct association with rainfall for four months of the year, rain time lag in July, and Gini index in February. The results demonstrate the importance of socio-environmental variables in the dynamics of dengue transmission and the relevance for the development of dengue control strategies.
Grape Extract and α-Tocopherol Effect in Cardiovascular Disease Model of Apo E -/- Mice
To verify the effect of consumption of grape extract isolated or combined with α-tocopherol supplementation on atherosclerosis model with Apo E -/- mice.