Ulrich H. Koszinowski Max von Pettenkofer Institute Biography Publications Institution JoVE Articles Ulrich H. Koszinowski has not added a biography. If you are Ulrich H. Koszinowski and would like to personalize this page please email our Author Liaison for assistance. Publications The Viral Chemokine MCK-2 of Murine Cytomegalovirus Promotes Infection As Part of a GH/gL/MCK-2 Complex PLoS Pathogens. Jul, 2013 | Pubmed ID: 23935483 Natural Killer Cells Are Required for Extramedullary Hematopoiesis Following Murine Cytomegalovirus Infection Cell Host & Microbe. May, 2013 | Pubmed ID: 23684305 Systemic and Local Infection Routes Govern Different Cellular Dissemination Pathways During Gammaherpesvirus Infection in Vivo Journal of Virology. Apr, 2013 | Pubmed ID: 23408606 Characterization of Conserved Region 2-deficient Mutants of the Cytomegalovirus Egress Protein PM53 Journal of Virology. Dec, 2012 | Pubmed ID: 22993161 The Polyomaviruses WUPyV and KIPyV: a Retrospective Quantitative Analysis in Patients Undergoing Hematopoietic Stem Cell Transplantation Virology Journal. 2012 | Pubmed ID: 22988938 Protection from Inflammatory Organ Damage in a Murine Model of Hemophagocytic Lymphohistiocytosis Using Treatment with IL-18 Binding Protein Frontiers in Immunology. 2012 | Pubmed ID: 22891066 A Beta-herpesvirus with Fluorescent Capsids to Study Transport in Living Cells PloS One. 2012 | Pubmed ID: 22792376 Cytomegalovirus Replicon-based Regulation of Gene Expression in Vitro and in Vivo PLoS Pathogens. 2012 | Pubmed ID: 22685399 A Cell Free Protein Fragment Complementation Assay for Monitoring the Core Interaction of the Human Cytomegalovirus Nuclear Egress Complex Antiviral Research. Jul, 2012 | Pubmed ID: 22580129 Degradation of Cellular Mir-27 by a Novel, Highly Abundant Viral Transcript is Important for Efficient Virus Replication in Vivo PLoS Pathogens. Feb, 2012 | Pubmed ID: 22346748 The Role of Cell Types in Cytomegalovirus Infection in Vivo European Journal of Cell Biology. Jan, 2012 | Pubmed ID: 21492952 Shedding Light on the Elusive Role of Endothelial Cells in Cytomegalovirus Dissemination PLoS Pathogens. Nov, 2011 | Pubmed ID: 22114552 Virus Progeny of Murine Cytomegalovirus Bacterial Artificial Chromosome PSM3fr Show Reduced Growth in Salivary Glands Due to a Fixed Mutation of MCK-2 Journal of Virology. Oct, 2011 | Pubmed ID: 21813614 M94 is Essential for the Secondary Envelopment of Murine Cytomegalovirus Journal of Virology. Sep, 2011 | Pubmed ID: 21715482 HCMV Spread and Cell Tropism Are Determined by Distinct Virus Populations PLoS Pathogens. 2011 | Pubmed ID: 21249233 Human Cytomegalovirus Disrupts the Major Histocompatibility Complex Class I Peptide-loading Complex and Inhibits Tapasin Gene Transcription Journal of Virology. Apr, 2011 | Pubmed ID: 21248040 Cytomegalovirus MicroRNAs Facilitate Persistent Virus Infection in Salivary Glands PLoS Pathogens. 2010 | Pubmed ID: 20976200 Dominant Negative Mutants of the Murine Cytomegalovirus M53 Gene Block Nuclear Egress and Inhibit Capsid Maturation Journal of Virology. Sep, 2010 | Pubmed ID: 20610730 Intact NKG2D-independent Function of NK Cells Chronically Stimulated with the NKG2D Ligand Rae-1 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2010 | Pubmed ID: 20530257 Systematic Analysis of Viral and Cellular MicroRNA Targets in Cells Latently Infected with Human Gamma-herpesviruses by RISC Immunoprecipitation Assay Cell Host & Microbe. Apr, 2010 | Pubmed ID: 20413099 Virology. A Vaccine Monkey Wrench? Science (New York, N.Y.). Apr, 2010 | Pubmed ID: 20360096 Dominant-negative Proteins in Herpesviruses - from Assigning Gene Function to Intracellular Immunization Viruses. Dec, 2009 | Pubmed ID: 21994555 Conserved Principles of Mammalian Transcriptional Regulation Revealed by RNA Half-life Nucleic Acids Research. Sep, 2009 | Pubmed ID: 19561200 Differential Susceptibility of RAE-1 Isoforms to Mouse Cytomegalovirus Journal of Virology. Aug, 2009 | Pubmed ID: 19494006 Cytomegalovirus MicroRNAs Virus Genes. Jun, 2009 | Pubmed ID: 19291384 Ly49P Recognition of Cytomegalovirus-infected Cells Expressing H2-Dk and CMV-encoded M04 Correlates with the NK Cell Antiviral Response The Journal of Experimental Medicine. Mar, 2009 | Pubmed ID: 19255146 High-resolution Gene Expression Profiling for Simultaneous Kinetic Parameter Analysis of RNA Synthesis and Decay RNA (New York, N.Y.). Sep, 2008 | Pubmed ID: 18658122 The Major Virus-producing Cell Type During Murine Cytomegalovirus Infection, the Hepatocyte, is Not the Source of Virus Dissemination in the Host Cell Host & Microbe. Apr, 2008 | Pubmed ID: 18407069 Dissection of the Antiviral NK Cell Response by MCMV Mutants Methods in Molecular Biology (Clifton, N.J.). 2008 | Pubmed ID: 18370152 Conditional Gene Expression Systems to Study Herpesvirus Biology in Vivo Medical Microbiology and Immunology. Jun, 2008 | Pubmed ID: 18324415 Dominant-negative FADD Rescues the in Vivo Fitness of a Cytomegalovirus Lacking an Antiapoptotic Viral Gene Journal of Virology. Mar, 2008 | Pubmed ID: 18094168 Engineering of Cytomegalovirus Genomes for Recombinant Live Herpesvirus Vaccines International Journal of Medical Microbiology : IJMM. Jan, 2008 | Pubmed ID: 17702650 Targeted Deletion of Regions Rich in Immune-evasive Genes from the Cytomegalovirus Genome As a Novel Vaccine Strategy Journal of Virology. Dec, 2007 | Pubmed ID: 17913824 Natural Killer Cells Promote Early CD8 T Cell Responses Against Cytomegalovirus PLoS Pathogens. Aug, 2007 | Pubmed ID: 17722980 Random Screening for Dominant-negative Mutants of the Cytomegalovirus Nuclear Egress Protein M50 Journal of Virology. Jun, 2007 | Pubmed ID: 17376929 Viral Interference with B7-1 Costimulation: a New Role for Murine Cytomegalovirus Fc Receptor-1 Journal of Immunology (Baltimore, Md. : 1950). Dec, 2006 | Pubmed ID: 17142739 Common and Specific Properties of Herpesvirus UL34/UL31 Protein Family Members Revealed by Protein Complementation Assay Journal of Virology. Dec, 2006 | Pubmed ID: 17005637 Coordinated Function of Murine Cytomegalovirus Genes Completely Inhibits CTL Lysis Journal of Immunology (Baltimore, Md. : 1950). Sep, 2006 | Pubmed ID: 16920962 The Herpesviral Fc Receptor Fcr-1 Down-regulates the NKG2D Ligands MULT-1 and H60 The Journal of Experimental Medicine. Aug, 2006 | Pubmed ID: 16831899 Functional Domains of Murine Cytomegalovirus Nuclear Egress Protein M53/p38 Journal of Virology. Jan, 2006 | Pubmed ID: 16352532 Frequent Coinfection of Cells Explains Functional in Vivo Complementation Between Cytomegalovirus Variants in the Multiply Infected Host Journal of Virology. Aug, 2005 | Pubmed ID: 16014912 Viruses Know It All: New Insights into IFN Networks Trends in Immunology. Jul, 2005 | Pubmed ID: 15922665 Use of a Murine Cytomegalovirus K181-derived Bacterial Artificial Chromosome As a Vaccine Vector for Immunocontraception Journal of Virology. Mar, 2005 | Pubmed ID: 15709020 Selective Down-regulation of the NKG2D Ligand H60 by Mouse Cytomegalovirus M155 Glycoprotein Journal of Virology. Mar, 2005 | Pubmed ID: 15709011 NK Cell Activation Through the NKG2D Ligand MULT-1 is Selectively Prevented by the Glycoprotein Encoded by Mouse Cytomegalovirus Gene M145 The Journal of Experimental Medicine. Jan, 2005 | Pubmed ID: 15642742 Conditional Cytomegalovirus Replication in Vitro and in Vivo Journal of Virology. Jan, 2005 | Pubmed ID: 15596841 Comprehensive Mutational Analysis of a Herpesvirus Gene in the Viral Genome Context Reveals a Region Essential for Virus Replication Journal of Virology. Aug, 2004 | Pubmed ID: 15254174 Gain of Virulence Caused by Loss of a Gene in Murine Cytomegalovirus Journal of Virology. Jul, 2004 | Pubmed ID: 15220428 Murine Cytomegalovirus Interference with Antigen Presentation Has Little Effect on the Size or the Effector Memory Phenotype of the CD8 T Cell Response Journal of Immunology (Baltimore, Md. : 1950). Jun, 2004 | Pubmed ID: 15153514 Mutagenesis of Viral BACs with Linear PCR Fragments (ET Recombination) Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 15024171 Expansion of Protective CD8+ T-cell Responses Driven by Recombinant Cytomegaloviruses Journal of Virology. Mar, 2004 | Pubmed ID: 14963122 The Limits of Protection by "memory" T Cells in Ig-/- Mice Persistently Infected with a Gamma-herpesvirus Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14764895 The Human Cytomegalovirus UL45 Gene Product is a Late, Virion-associated Protein and Influences Virus Growth at Low Multiplicities of Infection The Journal of General Virology. Dec, 2003 | Pubmed ID: 14645917 Vaccination of Mice with Bacteria Carrying a Cloned Herpesvirus Genome Reconstituted in Vivo Journal of Virology. Aug, 2003 | Pubmed ID: 12857893 Role of Murine Cytomegalovirus US22 Gene Family Members in Replication in Macrophages Journal of Virology. May, 2003 | Pubmed ID: 12719548 Dendritic Cells Under Influence of Mouse Cytomegalovirus Have a Physiologic Dual Role: to Initiate and to Restrict T Cell Activation The Journal of Infectious Diseases. Mar, 2003 | Pubmed ID: 12660946 Cloning of Herpesviral Genomes As Bacterial Artificial Chromosomes Reviews in Medical Virology. Mar-Apr, 2003 | Pubmed ID: 12627394 Memory Inflation: Continuous Accumulation of Antiviral CD8+ T Cells over Time Journal of Immunology (Baltimore, Md. : 1950). Feb, 2003 | Pubmed ID: 12574372 A Gammaherpesvirus G Protein-coupled Receptor Homologue is Required for Increased Viral Replication in Response to Chemokines and Efficient Reactivation from Latency Journal of Immunology (Baltimore, Md. : 1950). Jan, 2003 | Pubmed ID: 12496406 Effective Inhibition of K(b)- and D(b)-restricted Antigen Presentation in Primary Macrophages by Murine Cytomegalovirus Journal of Virology. Jan, 2003 | Pubmed ID: 12477835 Major Histocompatibility Complex Class I Allele-specific Cooperative and Competitive Interactions Between Immune Evasion Proteins of Cytomegalovirus The Journal of Experimental Medicine. Sep, 2002 | Pubmed ID: 12235213 The Human Cytomegalovirus Ribonucleotide Reductase Homolog UL45 is Dispensable for Growth in Endothelial Cells, As Determined by a BAC-cloned Clinical Isolate of Human Cytomegalovirus with Preserved Wild-type Characteristics Journal of Virology. Sep, 2002 | Pubmed ID: 12186938 Cytomegalovirus Recruitment of Cellular Kinases to Dissolve the Nuclear Lamina Science (New York, N.Y.). Aug, 2002 | Pubmed ID: 12161659 Herpesvirus Genetics Has Come of Age Trends in Microbiology. Jul, 2002 | Pubmed ID: 12110210 The Murine Cytomegalovirus Immunomodulatory Gene M152 Prevents Recognition of Infected Cells by M45-specific CTL but Does Not Alter the Immunodominance of the M45-specific CD8 T Cell Response in Vivo Journal of Immunology (Baltimore, Md. : 1950). Jul, 2002 | Pubmed ID: 12077265 MCMV Glycoprotein Gp40 Confers Virus Resistance to CD8+ T Cells and NK Cells in Vivo Nature Immunology. Jun, 2002 | Pubmed ID: 12021778 The Glycoprotein Gp48 of Murine CytomegalovirusL Proteasome-dependent Cytosolic Dislocation and Degradation The Journal of Biological Chemistry. Jan, 2002 | Pubmed ID: 11707434 Metabolic Labeling of Newly Transcribed RNA for High Resolution Gene Expression Profiling of RNA Synthesis, Processing and Decay in Cell Culture Bernd Rädle*1, Andrzej J. Rutkowski*2, Zsolt Ruzsics1, Caroline C. Friedel3, Ulrich H. Koszinowski1, Lars Dölken2 1Max von Pettenkofer Institute, 2Department of Medicine, University of Cambridge, 3Institute for Informatics, Ludwig-Maximilians-University Munich JoVE 50195 Biology
Metabolic Labeling of Newly Transcribed RNA for High Resolution Gene Expression Profiling of RNA Synthesis, Processing and Decay in Cell Culture Bernd Rädle*1, Andrzej J. Rutkowski*2, Zsolt Ruzsics1, Caroline C. Friedel3, Ulrich H. Koszinowski1, Lars Dölken2 1Max von Pettenkofer Institute, 2Department of Medicine, University of Cambridge, 3Institute for Informatics, Ludwig-Maximilians-University Munich JoVE 50195 Biology
