Uwe Christians iC42 Clinical Research and Development University of Colorado, Anschutz Medical Campus Biography Publications Institution JoVE Articles Uwe Christians has not added a biography. If you are Uwe Christians and would like to personalize this page please email our Author Liaison for assistance. Publications ANALYTICAL ASPECTS OF THE IMPLEMENTATION OF BIOMARKERS IN CLINICAL TRANSPLANTATION Therapeutic Drug Monitoring. Jul, 2015 | Pubmed ID: 26418704 Memory-updating Abrogates Extinction of Learned Immunosuppression Brain, Behavior, and Immunity. Sep, 2015 | Pubmed ID: 26386321 Pravastatin Therapy and Biomarker Changes in Children and Young Adults with Autosomal Dominant Polycystic Kidney Disease Clinical Journal of the American Society of Nephrology : CJASN. Sep, 2015 | Pubmed ID: 26224879 Long-term Cross-validation of Everolimus Therapeutic Drug Monitoring Assays: the Zortracker Study Therapeutic Drug Monitoring. Jun, 2015 | Pubmed ID: 25970506 Everolimus and Sirolimus in Transplantation-related but Different Expert Opinion on Drug Safety. Jul, 2015 | Pubmed ID: 25912929 A High-performance Liquid Chromatography-tandem Mass Spectrometry-based Targeted Metabolomics Kidney Dysfunction Marker Panel in Human Urine Clinica Chimica Acta; International Journal of Clinical Chemistry. Jun, 2015 | Pubmed ID: 25871999 Neurobehavioral Consequences of Small Molecule-drug Immunosuppression Neuropharmacology. Sep, 2015 | Pubmed ID: 25529273 Age-dependent Changes in Sirolimus Metabolite Formation in Patients with Neurofibromatosis Type 1 Therapeutic Drug Monitoring. Jun, 2015 | Pubmed ID: 25162215 Endothelial Dysfunction and Oxidative Stress in Polycystic Kidney Disease American Journal of Physiology. Renal Physiology. Dec, 2014 | Pubmed ID: 25234311 Fatty Acid Desaturation Index in Human Plasma: Comparison of Different Analytical Methodologies for the Evaluation of Diet Effects Analytical and Bioanalytical Chemistry. Oct, 2014 | Pubmed ID: 25116600 Inhibition of Calcineurin Combined with Dasatinib Has Direct and Indirect Anti-leukemia Effects Against BCR-ABL1(+) Leukemia American Journal of Hematology. Sep, 2014 | Pubmed ID: 24891015 Focus on MTOR Inhibitors and Tacrolimus in Renal Transplantation: Pharmacokinetics, Exposure-response Relationships, and Clinical Outcomes Transplant Immunology. Jun, 2014 | Pubmed ID: 24861504 Early Effect of Tidal Volume on Lung Injury Biomarkers in Surgical Patients with Healthy Lungs Anesthesiology. Sep, 2014 | Pubmed ID: 24809976 Mycophenolate Mofetil Enhances the Negative Effects of Sirolimus and Tacrolimus on Rat Kidney Cell Metabolism PloS One. 2014 | Pubmed ID: 24497939 CD73-dependent Generation of Adenosine and Endothelial Adora2b Signaling Attenuate Diabetic Nephropathy Journal of the American Society of Nephrology : JASN. Mar, 2014 | Pubmed ID: 24262796 Bioactive Lipid Mediators in Polycystic Kidney Disease Journal of Lipid Research. Dec, 2013 | Pubmed ID: 24343898 Cyclosporine Induces Endothelial Cell Release of Complement-activating Microparticles Journal of the American Society of Nephrology : JASN. Nov, 2013 | Pubmed ID: 24092930 Changes in Clearance, Volume and Bioavailability of Immunosuppressants when Given with HAART in HIV-1 Infected Liver and Kidney Transplant Recipients Biopharmaceutics & Drug Disposition. Nov, 2013 | Pubmed ID: 24030928 Quantification of the 5-lipoxygenase Inhibitor Zileuton in Human Plasma Using High Performance Liquid Chromatography-tandem Mass Spectrometry Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Oct, 2013 | Pubmed ID: 24029553 Effects of Lovastatin Treatment on the Metabolic Distributions in the Han:SPRD Rat Model of Polycystic Kidney Disease BMC Nephrology. 2013 | Pubmed ID: 23902712 Emerging Technologies: Polymer-free Phospholipid Encapsulated Sirolimus Nanocarriers for the Controlled Release of Drug from a Stent-plus-balloon or a Stand-alone Balloon Catheter EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology. May, 2013 | Pubmed ID: 23685303 Comparison of the Quantification of Acetaminophen in Plasma, Cerebrospinal Fluid and Dried Blood Spots Using High-performance Liquid Chromatography-tandem Mass Spectrometry Journal of Pharmaceutical and Biomedical Analysis. Sep, 2013 | Pubmed ID: 23670126 Multidrug Resistance-associated Protein 2 (MRP2/ABCC2) Haplotypes Significantly Affect the Pharmacokinetics of Tacrolimus in Kidney Transplant Recipients Clinical Pharmacokinetics. Sep, 2013 | Pubmed ID: 23633119 Early Increase in Alveolar Macrophage Prostaglandin 15d-PGJ2 Precedes Neutrophil Recruitment into Lungs of Cytokine-insufflated Rats Inflammation. Oct, 2013 | Pubmed ID: 23616184 Genetic and Structure-function Studies of Missense Mutations in Human Endothelial Lipase PloS One. 2013 | Pubmed ID: 23536757 Development and Validation of an LC-MS/MS Assay for the Quantification of the Trans-methylation Pathway Intermediates S-adenosylmethionine and S-adenosylhomocysteine in Human Plasma Clinica Chimica Acta; International Journal of Clinical Chemistry. Jun, 2013 | Pubmed ID: 23499573 Proteomics and Metabolomics in Renal Transplantation-quo Vadis? Transplant International : Official Journal of the European Society for Organ Transplantation. Mar, 2013 | Pubmed ID: 23350848 Concentration of Tacrolimus and Major Metabolites in Kidney Transplant Recipients As a Function of Diabetes Mellitus and Cytochrome P450 3A Gene Polymorphism Xenobiotica; the Fate of Foreign Compounds in Biological Systems. Jul, 2013 | Pubmed ID: 23278282 A Multi-center Phase Ib Study of Oxaliplatin (NSC#266046) in Combination with Fluorouracil and Leucovorin in Pediatric Patients with Advanced Solid Tumors Pediatric Blood & Cancer. Feb, 2013 | Pubmed ID: 23024067 Association of DJ-1/PTEN/AKT- and ASK1/p38-mediated Cell Signalling with Ischaemic Cardiomyopathy Cardiovascular Research. Jan, 2013 | Pubmed ID: 23015639 Neurobehavioural Activation During Peripheral Immunosuppression The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). Feb, 2013 | Pubmed ID: 22217400 Mass Spectrometry-Based Multiplexing for the Analysis of Biomarkers in Drug Development and Clinical Diagnostics- How Much is Too Much? Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science. Nov, 2012 | Pubmed ID: 23645936 Fibronectin-integrin Signaling is Required for L-glutamine's Protection Against Gut Injury PloS One. 2012 | Pubmed ID: 23185570 Everolimus and Sirolimus in Combination with Cyclosporine Have Different Effects on Renal Metabolism in the Rat PloS One. 2012 | Pubmed ID: 23118926 Low-salt Diet and Cyclosporine Nephrotoxicity: Changes in Kidney Cell Metabolism Journal of Proteome Research. Nov, 2012 | Pubmed ID: 23057591 MF101: a Multi-component Botanical Selective Estrogen Receptor Beta Modulator for the Treatment of Menopausal Vasomotor Symptoms Expert Opinion on Investigational Drugs. Jul, 2012 | Pubmed ID: 22616988 Equilibrative Nucleoside Transporter 1 (ENT1) Regulates Postischemic Blood Flow During Acute Kidney Injury in Mice The Journal of Clinical Investigation. Feb, 2012 | Pubmed ID: 22269324 Influence of SLCO1B1 Polymorphisms on the Drug-drug Interaction Between Darunavir/ritonavir and Pravastatin Journal of Clinical Pharmacology. Nov, 2012 | Pubmed ID: 22174437 A High-throughput U-HPLC-MS/MS Assay for the Quantification of Mycophenolic Acid and Its Major Metabolites Mycophenolic Acid Glucuronide and Mycophenolic Acid Acyl-glucuronide in Human Plasma and Urine Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Feb, 2012 | Pubmed ID: 21839692 A Low Blood Volume LC-MS/MS Assay for the Quantification of Fentanyl and Its Major Metabolites Norfentanyl and Despropionyl Fentanyl in Children Journal of Separation Science. Dec, 2011 | Pubmed ID: 21916010 Structural Identification of SAR-943 Metabolites Generated by Human Liver Microsomes in Vitro Using Mass Spectrometry in Combination with Analysis of Fragmentation Patterns Journal of Mass Spectrometry : JMS. Jul, 2011 | Pubmed ID: 21671437 Bezielle (BZL101)-induced Oxidative Stress Damage Followed by Redistribution of Metabolic Fluxes in Breast Cancer Cells: a Combined Proteomic and Metabolomic Study International Journal of Cancer. Journal International Du Cancer. Dec, 2011 | Pubmed ID: 21509784 How Unbiased is Non-targeted Metabolomics and is Targeted Pathway Screening the Solution? Current Pharmaceutical Biotechnology. Jul, 2011 | Pubmed ID: 21466457 A Sensitive Assay for the Quantification of Morphine and Its Active Metabolites in Human Plasma and Dried Blood Spots Using High-performance Liquid Chromatography-tandem Mass Spectrometry Analytical and Bioanalytical Chemistry. May, 2011 | Pubmed ID: 21400080 Liquid Chromatography and Mass Spectrometry in Food Allergen Detection Journal of Food Protection. Feb, 2011 | Pubmed ID: 21333155 Quantification of 15-F2t-isoprostane in Human Plasma and Urine: Results from Enzyme-linked Immunoassay and Liquid Chromatography/tandem Mass Spectrometry Cannot Be Compared Rapid Communications in Mass Spectrometry : RCM. Feb, 2011 | Pubmed ID: 21259353 Biomarkers of Immunosuppressant Organ Toxicity After Transplantation: Status, Concepts and Misconceptions Expert Opinion on Drug Metabolism & Toxicology. Feb, 2011 | Pubmed ID: 21241200 Pharmacokinetics of Single-dose Intravenous Ketorolac in Infants Aged 2-11 Months Anesthesia and Analgesia. Mar, 2011 | Pubmed ID: 21233498 Interpreting Mammalian Target of Rapamycin and Cell Growth Inhibition in a Genetically Engineered Mouse Model of Nf1-deficient Astrocytes Molecular Cancer Therapeutics. Feb, 2011 | Pubmed ID: 21216928 Urinary Catalytic Iron in Patients with Type 2 Diabetes Without Microalbuminuria--a Substudy of the ACCORD Trial Clinical Chemistry. Feb, 2011 | Pubmed ID: 21159897 Age and Sex Differences in the Effects of the Immunosuppressants Cyclosporine, Sirolimus and Everolimus on Rat Brain Metabolism Neurotoxicology. Jan, 2011 | Pubmed ID: 21075140 The Pharmacokinetics of Biolimus A9 After Elution from the BioMatrix II Stent in Patients with Coronary Artery Disease: the Stealth PK Study European Journal of Clinical Pharmacology. Apr, 2011 | Pubmed ID: 20963405 Randomized, Double-blind, Placebo-controlled, Single Intravenous Dose-escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of the Novel Coronary Smooth Muscle Cell Proliferation Inhibitor Biolimus A9 in Healthy Individuals Journal of Clinical Pharmacology. Jan, 2011 | Pubmed ID: 20305057 Opioid Pharmacogenomics Using a Twin Study Paradigm: Methods and Procedures for Determining Familial Aggregation and Heritability Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies. Oct, 2010 | Pubmed ID: 20874462 Toxicodynamic Effects of Ciclosporin Are Reflected by Metabolite Profiles in the Urine of Healthy Individuals After a Single Dose British Journal of Clinical Pharmacology. Aug, 2010 | Pubmed ID: 20653677 Continuous Administration of a Selective Alpha7 Nicotinic Partial Agonist, DMXBA, Improves Sensory Inhibition Without Causing Tachyphylaxis or Receptor Upregulation in DBA/2 Mice Brain Research. Sep, 2010 | Pubmed ID: 20599427 Polymer-free Biolimus A9-coated Stent Demonstrates More Sustained Intimal Inhibition, Improved Healing, and Reduced Inflammation Compared with a Polymer-coated Sirolimus-eluting Cypher Stent in a Porcine Model Circulation. Cardiovascular Interventions. Apr, 2010 | Pubmed ID: 20407114 Characterization of Potential Allergens in Fenugreek (Trigonella Foenum-graecum) Using Patient Sera and MS-based Proteomic Analysis Journal of Proteomics. May, 2010 | Pubmed ID: 20219717 Effects of Lovastatin on Breast Cancer Cells: a Proteo-metabonomic Study Breast Cancer Research : BCR. 2010 | Pubmed ID: 20205716 Bioequivalence Testing of Immunosuppressants: Concepts and Misconceptions Kidney International. Supplement. Mar, 2010 | Pubmed ID: 20150904 Immunosuppressant Neurotoxicity in Rat Brain Models: Oxidative Stress and Cellular Metabolism Chemical Research in Toxicology. Mar, 2010 | Pubmed ID: 20148532 Association of Immunosuppressant-induced Protein Changes in the Rat Kidney with Changes in Urine Metabolite Patterns: a Proteo-metabonomic Study Journal of Proteome Research. Feb, 2010 | Pubmed ID: 19994912 Identification and Characterization of a Bacterial Cytochrome P450 for the Metabolism of Diclofenac Applied Microbiology and Biotechnology. Jan, 2010 | Pubmed ID: 19636551 Consequences of Delayed Pump Infusion Line Change in Patients with Type 1 Diabetes Mellitus Treated with Continuous Subcutaneous Insulin Infusion Journal of Diabetes and Its Complications. Mar-Apr, 2010 | Pubmed ID: 19395280 Development and Validation of a Semi-automated Assay for the Highly Sensitive Quantification of Biolimus A9 in Human Whole Blood Using High-performance Liquid Chromatography-tandem Mass Spectrometry Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Nov, 2009 | Pubmed ID: 19762292 Irradiation Alters Selection for Oncogenic Mutations in Hematopoietic Progenitors Cancer Research. Sep, 2009 | Pubmed ID: 19738065 Metabolic Characteristics of Imatinib Resistance in Chronic Myeloid Leukaemia Cells British Journal of Pharmacology. Sep, 2009 | Pubmed ID: 19663881 Development and Validation of a Sensitive Assay for the Quantification of Imatinib Using LC/LC-MS/MS in Human Whole Blood and Cell Culture Biomedical Chromatography : BMC. Dec, 2009 | Pubmed ID: 19517424 Enhanced Leukocyte HIF-1alpha and HIF-1 DNA Binding in Humans After Rapid Ascent to 4300 M Free Radical Biology & Medicine. Jun, 2009 | Pubmed ID: 19303436 Metabolic Profiles in Urine Reflect Nephrotoxicity of Sirolimus and Cyclosporine Following Rat Kidney Transplantation Nephron. Experimental Nephrology. 2009 | Pubmed ID: 19293597 Urine Metabolites Reflect Time-dependent Effects of Cyclosporine and Sirolimus on Rat Kidney Function Chemical Research in Toxicology. Jan, 2009 | Pubmed ID: 19099400 Competitive Substrates for P-glycoprotein and Organic Anion Protein Transporters Differentially Reduce Blood Organ Transport of Fentanyl and Loperamide: Pharmacokinetics and Pharmacodynamics in Sprague-Dawley Rats Anesthesia and Analgesia. Jan, 2009 | Pubmed ID: 19095843 Characterization of Sirolimus Metabolites in Pediatric Solid Organ Transplant Recipients Pediatric Transplantation. Feb, 2009 | Pubmed ID: 18482220 The Pharmacokinetics of Biolimus A9 After Elution from the Nobori Stent in Patients with Coronary Artery Disease: the NOBORI PK Study Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions. Dec, 2008 | Pubmed ID: 19016466 An Automated, Highly Sensitive LC-MS/MS Assay for the Quantification of the Opiate Antagonist Naltrexone and Its Major Metabolite 6beta-naltrexol in Dog and Human Plasma Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Oct, 2008 | Pubmed ID: 18805072 Oxidative in Vitro Metabolism of Liquiritigenin, a Bioactive Compound Isolated from the Chinese Herbal Selective Estrogen Beta-receptor Agonist MF101 Drug Metabolism and Disposition: the Biological Fate of Chemicals. Nov, 2008 | Pubmed ID: 18669586 A Metabonomic and Proteomic Analysis of Changes in IMCD3 Cells Chronically Adapted to Hypertonicity Nephron. Physiology. 2008 | Pubmed ID: 18460876 Toxicodynamic Therapeutic Drug Monitoring of Immunosuppressants: Promises, Reality, and Challenges Therapeutic Drug Monitoring. Apr, 2008 | Pubmed ID: 18367974 Pharmacokinetics of Mycophenolate Mofetil and Sirolimus in Children Therapeutic Drug Monitoring. Apr, 2008 | Pubmed ID: 18367972 Crossreactivity of Isolated Everolimus Metabolites with the Innofluor Certican Immunoassay for Therapeutic Drug Monitoring of Everolimus Therapeutic Drug Monitoring. Dec, 2007 | Pubmed ID: 18043471 Identification of Everolimus Metabolite Patterns in Trough Blood Samples of Kidney Transplant Patients Therapeutic Drug Monitoring. Oct, 2007 | Pubmed ID: 17898649 Comparison of Lung Proteome Profiles in Two Rodent Models of Pulmonary Arterial Hypertension Proteomics. Jul, 2007 | Pubmed ID: 17623304 Serotonin Transporter Protein in Pulmonary Hypertensive Rats Treated with Atorvastatin American Journal of Physiology. Lung Cellular and Molecular Physiology. Sep, 2007 | Pubmed ID: 17575010 Assessment and Validation of the MS/MS Fragmentation Patterns of the Macrolide Immunosuppressant Everolimus Journal of Mass Spectrometry : JMS. Jun, 2007 | Pubmed ID: 17511017 Pharmacokinetics of Enteric-coated Mycophenolate Sodium in Stable Liver Transplant Recipients Clinical Transplantation. May-Jun, 2007 | Pubmed ID: 17488394 Development and Validation of an Assay for the Quantification of 11 Nucleotides Using LC/LC-electrospray Ionization-MS Analytical Biochemistry. Jun, 2007 | Pubmed ID: 17475198 HPLC-atmospheric Pressure Chemical Ionization MS/MS for Quantification of 15-F2t-isoprostane in Human Urine and Plasma Clinical Chemistry. Mar, 2007 | Pubmed ID: 17259231 Prolonged Survival of Porcine Hepatocytes in Cynomolgus Monkeys Gastroenterology. Jan, 2007 | Pubmed ID: 17241882 Quantification of Isoniazid and Acetylisoniazid in Rat Plasma and Alveolar Macrophages by Liquid Chromatography-tandem Mass Spectrometry with On-line Extraction Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. Mar, 2007 | Pubmed ID: 17070115 Cyclosporin Twice or Three Times Daily Dosing in Pediatric Transplant Patients - It is Not the Same! Pediatric Transplantation. Dec, 2006 | Pubmed ID: 17096765 Pharmacokinetics of Pyridostigmine in a Child with Postural Tachycardia Syndrome Pediatrics. Nov, 2006 | Pubmed ID: 17015495 Impact of Organ Preservation Using HTK for Graft Flush and Subsequent Storage in UW in Rat Kidney Transplantation European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes. 2006 | Pubmed ID: 16847398 Unexpectedly High Exposure to Enteric-coated Mycophenolate Sodium Upon Once-daily Dosing Pediatric Nephrology (Berlin, Germany). Aug, 2006 | Pubmed ID: 16721583 Risk of Impaired Coagulation in Warfarin Patients Ascending to Altitude (>2400 M) High Altitude Medicine & Biology. 2006 | Pubmed ID: 16544965 Prolonged Diabetes Reversal After Intraportal Xenotransplantation of Wild-type Porcine Islets in Immunosuppressed Nonhuman Primates Nature Medicine. Mar, 2006 | Pubmed ID: 16491083 Active Drug Transport of Immunosuppressants: New Insights for Pharmacokinetics and Pharmacodynamics Therapeutic Drug Monitoring. Feb, 2006 | Pubmed ID: 16418692 Functional Interactions Between P-glycoprotein and CYP3A in Drug Metabolism Expert Opinion on Drug Metabolism & Toxicology. Dec, 2005 | Pubmed ID: 16863430 Biomarkers for Toxicodynamic Monitoring of Immunosuppressants: NMR-based Quantitative Metabonomics of the Blood Therapeutic Drug Monitoring. Dec, 2005 | Pubmed ID: 16404806 Development and Validation of a High-throughput Assay for Quantification of the Proliferation Inhibitor ABT-578 Using LC/LC-MS/MS in Blood and Tissue Samples Therapeutic Drug Monitoring. Dec, 2005 | Pubmed ID: 16306853 Microparticle-based Lung Delivery of INH Decreases INH Metabolism and Targets Alveolar Macrophages Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2005 | Pubmed ID: 16009444 Cyclosporine Pharmacokinetics and Dosing Modifications in Human Immunodeficiency Virus-infected Liver and Kidney Transplant Recipients Transplantation. Jul, 2005 | Pubmed ID: 16003227 Adding Sirolimus to Tacrolimus-based Immunosuppression in Pediatric Renal Transplant Recipients Reduces Tacrolimus Exposure American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Aug, 2005 | Pubmed ID: 15996252 Greater Free Plasma VEGF and Lower Soluble VEGF Receptor-1 in Acute Mountain Sickness Journal of Applied Physiology (Bethesda, Md. : 1985). May, 2005 | Pubmed ID: 15649874 The Effect of Soluble Complement Receptor Type 1 on Acute Humoral Xenograft Rejection in HDAF-transgenic Pig-to-primate Life-supporting Kidney Xenografts Xenotransplantation. Jan, 2005 | Pubmed ID: 15598270 Cyclosporine Toxicity in Immunosuppressed Streptozotocin-diabetic Nonhuman Primates Toxicology. Feb, 2005 | Pubmed ID: 15590127 Automated, Fast, and Sensitive Quantification of Drugs in Human Plasma by LC/LC-MS: Quantification of 6 Protease Inhibitors and 3 Nonnucleoside Transcriptase Inhibitors Therapeutic Drug Monitoring. Oct, 2004 | Pubmed ID: 15385839 Alterations in Glucose Metabolism by Cyclosporine in Rat Brain Slices Link to Oxidative Stress: Interactions with MTOR Inhibitors British Journal of Pharmacology. Oct, 2004 | Pubmed ID: 15339861 Transport Proteins and Intestinal Metabolism: P-glycoprotein and Cytochrome P4503A Therapeutic Drug Monitoring. Apr, 2004 | Pubmed ID: 15228147 Biochemical Mechanisms of Cyclosporine Neurotoxicity Molecular Interventions. Apr, 2004 | Pubmed ID: 15087483 Preliminary in Vivo Pharmacokinetic and Pharmacodynamic Evaluation of a Novel Calcineurin-independent Inhibitor of NFAT Transplant International : Official Journal of the European Society for Organ Transplantation. Mar, 2004 | Pubmed ID: 14735234 CYP3A4-transfected Caco-2 Cells As a Tool for Understanding Biochemical Absorption Barriers: Studies with Sirolimus and Midazolam The Journal of Pharmacology and Experimental Therapeutics. Jan, 2004 | Pubmed ID: 14569063 Pharmacokinetic Interactions Between Cyclosporine and Protease Inhibitors in HIV+ Subjects Drug Metabolism and Pharmacokinetics. 2003 | Pubmed ID: 15618725 Transplantation: Toxicokinetics and Mechanisms of Toxicity of Cyclosporine and Macrolides Current Opinion in Investigational Drugs (London, England : 2000). Nov, 2003 | Pubmed ID: 14758767 Single Dose of Glutamine Enhances Myocardial Tissue Metabolism, Glutathione Content, and Improves Myocardial Function After Ischemia-reperfusion Injury JPEN. Journal of Parenteral and Enteral Nutrition. Nov-Dec, 2003 | Pubmed ID: 14621120 Sirolimus (rapamycin) Monotherapy Prevents Graft Vascular Disease in Nonhuman Primate Recipients of Orthotopic Aortic Allografts Circulation. May, 2003 | Pubmed ID: 12719285 Cyclosporine Can Increase Isoflurane MAC Anesthesia and Analgesia. Oct, 2002 | Pubmed ID: 12351270 Ultrasound-induced Mild Hyperthermia As a Novel Approach to Increase Drug Uptake in Brain Microvessel Endothelial Cells Pharmaceutical Research. Aug, 2002 | Pubmed ID: 12240937 Mechanisms of Clinically Relevant Drug Interactions Associated with Tacrolimus Clinical Pharmacokinetics. 2002 | Pubmed ID: 12190331 Close Association Between the Reduction in Myocardial Energy Metabolism and Infarct Size: Dose-response Assessment of Cyclosporine The Journal of Pharmacology and Experimental Therapeutics. Sep, 2002 | Pubmed ID: 12183671 Comparison of the Effects of Cyclosporin a on the Metabolism of Perfused Rat Brain Slices During Normoxia and Hypoxia Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Mar, 2002 | Pubmed ID: 11891440 LC-MS / MS kullanarak Kurutulmuş Kan Spotlar Immünosupresan Tacrolimus Niceleme Touraj Shokati1, Nicholas Bodenberger1, Holly Gadpaille1, Björn Schniedewind1, Alexander A. Vinks2, Wenlei Jiang3, Rita R. Alloway4, Uwe Christians1 1iC42 Clinical Research and Development, University of Colorado, Anschutz Medical Campus, 2Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, 3Food and Drug Administration (FDA), Center of Drug Evaluation Research - Office of Generic Drugs, 4Transplant Clinical Research, University of Cincinnati Medicine
LC-MS / MS kullanarak Kurutulmuş Kan Spotlar Immünosupresan Tacrolimus Niceleme Touraj Shokati1, Nicholas Bodenberger1, Holly Gadpaille1, Björn Schniedewind1, Alexander A. Vinks2, Wenlei Jiang3, Rita R. Alloway4, Uwe Christians1 1iC42 Clinical Research and Development, University of Colorado, Anschutz Medical Campus, 2Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, 3Food and Drug Administration (FDA), Center of Drug Evaluation Research - Office of Generic Drugs, 4Transplant Clinical Research, University of Cincinnati Medicine
