Wilfred R. Hagen Department of Biotechnology Delft University of Technology Biography Publications Institution JoVE Articles Wilfred R. Hagen has not added a biography. If you are Wilfred R. Hagen and would like to personalize this page please email our Author Liaison for assistance. Publications The Amyloid Precursor Protein (APP) Does Not Have a Ferroxidase Site in Its E2 Domain PloS One. 2013 | Pubmed ID: 23977245 A Conserved Tyrosine in Ferritin is a Molecular Capacitor Chembiochem : a European Journal of Chemical Biology. Jun, 2013 | Pubmed ID: 23737293 Broadband Transmission EPR Spectroscopy PloS One. 2013 | Pubmed ID: 23555819 Biochemical Similarities and Differences Between the Catalytic [4Fe-4S] Cluster Containing Fumarases FumA and FumB from Escherichia Coli PloS One. 2013 | Pubmed ID: 23405168 Phosphate Accelerates Displacement of Fe(III) by Fe(II) in the Ferroxidase Center of Pyrococcus Furiosus Ferritin FEBS Letters. Jan, 2013 | Pubmed ID: 23247211 De Novo Design, Synthesis and Characterisation of MP3, a New Catalytic Four-helix Bundle Hemeprotein Chemistry (Weinheim an Der Bergstrasse, Germany). Dec, 2012 | Pubmed ID: 23150230 The Catalytic Center of Ferritin Regulates Iron Storage Via Fe(II)-Fe(III) Displacement Nature Chemical Biology. Nov, 2012 | Pubmed ID: 23001032 Microbial Metalloproteomes Explored Using MIRAGE Chemistry & Biodiversity. Sep, 2012 | Pubmed ID: 22976984 A Synthetic Peptide with the Putative Iron Binding Motif of Amyloid Precursor Protein (APP) Does Not Catalytically Oxidize Iron PloS One. 2012 | Pubmed ID: 22916096 A Novel Mechanism of Iron-core Formation by Pyrococcus Furiosus Archaeoferritin, a Member of an Uncharacterized Branch of the Ferritin-like Superfamily Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Aug, 2012 | Pubmed ID: 22739810 Exploring the Microbial Metalloproteome Using MIRAGE Metallomics : Integrated Biometal Science. Dec, 2011 | Pubmed ID: 22094925 A Molecular Basis for Tungstate Selectivity in Prokaryotic ABC Transport Systems Journal of Bacteriology. Sep, 2011 | Pubmed ID: 21784948 Inhibition and Stimulation of Formation of the Ferroxidase Center and the Iron Core in Pyrococcus Furiosus Ferritin Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Nov, 2010 | Pubmed ID: 20582559 Reversible Biological Birch Reduction at an Extremely Low Redox Potential Journal of the American Chemical Society. Jul, 2010 | Pubmed ID: 20578740 Molybdenum Incorporation in Tungsten Aldehyde Oxidoreductase Enzymes from Pyrococcus Furiosus Journal of Bacteriology. Aug, 2010 | Pubmed ID: 20562313 Development of a Bionanotechnological Phosphate Removal System with Thermostable Ferritin Biotechnology and Bioengineering. Apr, 2010 | Pubmed ID: 19953676 The Tungsten Metallome of Pyrococcus Furiosus Metallomics : Integrated Biometal Science. Sep, 2009 | Pubmed ID: 21305143 Metallomic EPR Spectroscopy Metallomics : Integrated Biometal Science. Sep, 2009 | Pubmed ID: 21305141 One- and Two-electron Reduction of Molybdate Reversibly Bound to the Archaeal Tungstate/molybdate Transporter WtpA Dalton Transactions (Cambridge, England : 2003). Oct, 2009 | Pubmed ID: 19789769 Catalysis of Iron Core Formation in Pyrococcus Furiosus Ferritin Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Nov, 2009 | Pubmed ID: 19623480 Identification of Two [4Fe-4S]-cluster-containing Hydro-lyases from Pyrococcus Furiosus Microbiology (Reading, England). Sep, 2009 | Pubmed ID: 19520720 Oleate Hydratase Catalyzes the Hydration of a Nonactivated Carbon-carbon Bond Journal of Bacteriology. Aug, 2009 | Pubmed ID: 19465645 Voltammetry of Pyrococcus Furiosus Ferritin: Dependence of Iron Release Rate on Mediator Potential Dalton Transactions (Cambridge, England : 2003). Apr, 2009 | Pubmed ID: 19333508 A Thermostable Hybrid Cluster Protein from Pyrococcus Furiosus: Effects of the Loss of a Three Helix Bundle Subdomain Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Jun, 2009 | Pubmed ID: 19241093 Development of a Generic Approach to Native Metalloproteomics: Application to the Quantitative Identification of Soluble Copper Proteins in Escherichia Coli Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. May, 2009 | Pubmed ID: 19205756 Reinvestigation of the Steady-state Kinetics and Physiological Function of the Soluble NiFe-hydrogenase I of Pyrococcus Furiosus Journal of Bacteriology. Mar, 2008 | Pubmed ID: 18156274 Function of MoaB Proteins in the Biosynthesis of the Molybdenum and Tungsten Cofactors Biochemistry. Jan, 2008 | Pubmed ID: 18154309 A Steady-state and Pre-steady-state Kinetics Study of the Tungstoenzyme Formaldehyde Ferredoxin Oxidoreductase from Pyrococcus Furiosus Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Jan, 2008 | Pubmed ID: 17899221 Iron(III)-catecholato Complexes As Structural and Functional Models of the Intradiol-cleaving Catechol Dioxygenases Inorganic Chemistry. Oct, 2007 | Pubmed ID: 17722878 Crystal Structure of the Ferritin from the Hyperthermophilic Archaeal Anaerobe Pyrococcus Furiosus Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Jun, 2007 | Pubmed ID: 17541801 Modeling the 2-His-1-carboxylate Facial Triad: Iron-catecholato Complexes As Structural and Functional Models of the Extradiol Cleaving Dioxygenases Journal of the American Chemical Society. Feb, 2007 | Pubmed ID: 17266307 EPR Studies of Recombinant Horse L-chain Apoferritin and Its Mutant (E 53,56,57,60 Q) with Haemin Biometals : an International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine. Feb, 2007 | Pubmed ID: 16988881 EPR Spectroscopy As a Probe of Metal Centres in Biological Systems Dalton Transactions (Cambridge, England : 2003). Oct, 2006 | Pubmed ID: 16981015 Tungsten Transport Protein A (WtpA) in Pyrococcus Furiosus: the First Member of a New Class of Tungstate and Molybdate Transporters Journal of Bacteriology. Sep, 2006 | Pubmed ID: 16952940 Redox Chemistry of Tungsten and Iron-sulfur Prosthetic Groups in Pyrococcus Furiosus Formaldehyde Ferredoxin Oxidoreductase Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Nov, 2006 | Pubmed ID: 16924554 Pyrococcus Furiosus 4Fe-ferredoxin, Chemisorbed on Gold, Exhibits Gated Reduction and Ionic Strength Dependent Dimerization Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Jul, 2006 | Pubmed ID: 16791647 Evidence Supporting a Cis-enediol-based Mechanism for Pyrococcus Furiosus Phosphoglucose Isomerase Journal of Molecular Biology. May, 2006 | Pubmed ID: 16580686 Computational Study of Ground-state Chiral Induction in Small Peptides: Comparison of the Relative Stability of Selected Amino Acid Dimers and Oligomers in Homochiral and Heterochiral Combinations Journal of Computational Chemistry. May, 2006 | Pubmed ID: 16541426 A Highly Thermostable Ferritin from the Hyperthermophilic Archaeal Anaerobe Pyrococcus Furiosus Extremophiles : Life Under Extreme Conditions. Apr, 2006 | Pubmed ID: 16341820 Unprecedented Stable Aqueous Semiquinone Methide Radical Formation Interferes with Adsorptive Cathodic Stripping Voltammetry of Cobalt Methyl Thymol Blue Talanta. Sep, 2005 | Pubmed ID: 18970212 Expression, Purification, Crystallization and Preliminary Crystallographic Analysis of a Stand-alone RAM Domain with Hydrolytic Activity from the Hyperthermophile Pyrococcus Furiosus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. Oct, 2005 | Pubmed ID: 16511194 Crystallization and Preliminary X-ray Characterization of a Ferritin from the Hyperthermophilic Archaeon and Anaerobe Pyrococcus Furiosus Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. May, 2005 | Pubmed ID: 16511080 WOR5, a Novel Tungsten-containing Aldehyde Oxidoreductase from Pyrococcus Furiosus with a Broad Substrate Specificity Journal of Bacteriology. Oct, 2005 | Pubmed ID: 16199576 The Dinuclear Iron-oxo Ferroxidase Center of Pyrococcus Furiosus Ferritin is a Stable Prosthetic Group with Unexpectedly High Reduction Potentials FEBS Letters. Aug, 2005 | Pubmed ID: 16107254 EPR Analysis of Multiple Forms of [4Fe-4S](3+) Clusters in HiPIPs Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Jun, 2005 | Pubmed ID: 15889286 A Three-component Dicamba O-demethylase from Pseudomonas Maltophilia, Strain DI-6: Purification and Characterization Archives of Biochemistry and Biophysics. May, 2005 | Pubmed ID: 15820213 Purification and Characterization of the Tungsten Enzyme Aldehyde:ferredoxin Oxidoreductase from the Hyperthermophilic Denitrifier Pyrobaculum Aerophilum Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. May, 2005 | Pubmed ID: 15772818 Tuning the Setup of Sputter-coated Multilayers in Nanocluster-based Signal-enhancing Biochips for Optimal Performance in Protein and DNA Assays Journal of Nanoscience and Nanotechnology. Jan-Feb, 2004 | Pubmed ID: 15112550 Redox Characteristics of the Tungsten DMSO Reductase of Rhodobacter Capsulatus FEBS Letters. Dec, 2003 | Pubmed ID: 14675782 Characterization of the Corrinoid Iron-sulfur Protein Tetrachloroethene Reductive Dehalogenase of Dehalobacter Restrictus Applied and Environmental Microbiology. Aug, 2003 | Pubmed ID: 12902251 Reduced Hybrid Cluster Proteins (HCP) from Desulfovibrio Desulfuricans ATCC 27774 and Desulfovibrio Vulgaris (Hildenborough): X-ray Structures at High Resolution Using Synchrotron Radiation Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. May, 2003 | Pubmed ID: 12764602 Two W-containing Formate Dehydrogenases (CO2-reductases) Involved in Syntrophic Propionate Oxidation by Syntrophobacter Fumaroxidans European Journal of Biochemistry / FEBS. Jun, 2003 | Pubmed ID: 12755703 Characterization of the Chlorate Reductase from Pseudomonas Chloritidismutans Journal of Bacteriology. May, 2003 | Pubmed ID: 12730181 Deuterium Isotope Effect on Enantioselectivity in the Comamonas Testosteroni Quinohemoprotein Alcohol Dehydrogenase-catalyzed Kinetic Resolution of Rac-2,2-dimethyl-4-hydroxymethyl-1,3-dioxolane, Solketal Biochimica Et Biophysica Acta. Apr, 2003 | Pubmed ID: 12686148 Spectroscopic Characterization and Ligand-binding Properties of Chlorite Dismutase from the Chlorate Respiring Bacterial Strain GR-1 European Journal of Biochemistry / FEBS. Oct, 2002 | Pubmed ID: 12354122 Hybrid Cluster Proteins (HCPs) from Desulfovibrio Desulfuricans ATCC 27774 and Desulfovibrio Vulgaris (Hildenborough): X-ray Structures at 1.25 A Resolution Using Synchrotron Radiation Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Apr, 2002 | Pubmed ID: 11941509 EPR Monitored Redox Titration of the Cofactors of Saccharomyces cerevisiae Nar1 Peter-Leon Hagedoorn1, Laura van der Weel1, Wilfred R. Hagen1 1Department of Biotechnology, Delft University of Technology JoVE 51611 Biology
EPR Monitored Redox Titration of the Cofactors of Saccharomyces cerevisiae Nar1 Peter-Leon Hagedoorn1, Laura van der Weel1, Wilfred R. Hagen1 1Department of Biotechnology, Delft University of Technology JoVE 51611 Biology