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Articles by Wolfgang Hübner in JoVE

 JoVE Immunology and Infection

Visualizing Cell-to-cell Transfer of HIV using Fluorescent Clones of HIV and Live Confocal Microscopy


JoVE 2061 10/07/2010

1Division of Infectious Diseases, Department of Medicine, Immunology Institute, Mount Sinai School of Medicine, 2NSF Center for Biophotonics, University of California, Davis, 3Structural and Computational Biology Unit, European Molecular Biology Laboratory

This visualized experiment is a guide for utilizing a fluorescent molecular clone of HIV for live confocal imaging experiments.

Other articles by Wolfgang Hübner on PubMed

[Casuistics of Pigmented Purpuric Lichenoid Dermatitis Gougerot-Blum]

[DETECTION AND MEASUREMENT OF RADIOACTIVE SUBSTANCES IN THE HUMAN BODY]

Telemetry of the EEG and EMG in the Cat Under the Influence of Psychotropic Drugs

Telemetry of Cardiac Left Ventricular Pressure in Conscious Dogs

A fully implantable telemetric system for the measurement of cardiac left ventricular pressure and derived parameters in conscious dogs is presented. It provides the following advantages: ethical acceptability, scientific relevance, economical experimentation, avoidance of stress-induced situations for the animal, experiments without anaesthesia or sedation. The system has an operation time which allows the sequential pharmacological evaluation of a great number of drugs in individual dogs as has been shown by testing the effect of the positive inotropic agent, dobutamine, and the calcium antagonists, verapamil and nifedipine.

Regulation of Myocardial Blood Flow in Man During Strenuous Exercise and Severe Hypoxia

Myocardial blood flow has been studied in 7 trained and 7 untrained healthy volunteers by means of the argon method. Measurements were carried out at rest, during stepwise increase in arterial hypoxia down to 8.7 vol % and during heavy exercise comparable to 65% of delta VO2 max. Measurements were carried out during hemodynamic and respiratory steady state conditions. Hemodynamic parameters were measured or even monitored. It could be shown that myocardial blood flow, myocardial oxygen consumption and myocardial oxygen consumption per heart beat are less in the trained state compared to the untrained one. The differences are particularly pronounced during heavy exercise. The reaction of the coronary conductance vessels to acute arterial hypoxia is not influenced by training effects. The surplus of oxygen and substrates supplied to the heart by the coronary circulation is well maintained during exercise and hypoxia.

Treatment-induced Cortical Reorganization After Stroke in Humans

Injury-induced cortical reorganization is a widely recognized phenomenon. In contrast, there is almost no information on treatment-induced plastic changes in the human brain. The aim of the present study was to evaluate reorganization in the motor cortex of stroke patients that was induced with an efficacious rehabilitation treatment.

Development of One Experimental Module to Study the Modulation of the Propagation Velocity of Chemical Excitation Waves in Gel by Weak External Force (gravity)

Biological and chemical systems in which the pattern of flow of energy and matter imposes self-organization can be seen as examples of excitable media. One property of such media is the presence of excitation waves. The Belouzov-Zabotinsky(B-Z) reaction system and the retinal spreading depression wave are examples of experimental models of excitable media in which the influence of gravity can be studied. In this paper we describe one especial module constructed to test the influence of gravity in gels of the B-Z system. In the gel condition, convection effects are minimized. The results will be directly comparable to retinal experiments programmed by the same group and complete a series of investigations of systematic comparison of the modulation of chemical and biological excitation waves by weak external forces.

Education and Training of Young People Who Grew Up with Cochlear Implants

We want to provide new qualitative and quantitative data on the long-term impact of cochlear implantation (CI) on educational placement, vocational outcomes and employment status of hearing-impaired adolescents and young adults.

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