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In JoVE (1)
Other Publications (4)
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Articles by Yi Cheng in JoVE
גישור ממשק ביו אלקטרונית עם Biofabrication
Tanya Gordonov*1, Benjamin Liba*2, Jessica L. Terrell*1, Yi Cheng3, Xiaolong Luo2, Gregory F. Payne1, William E. Bentley1
1Fischell Department of Bioengineering, University of Maryland, 2Institute for Bioscience and Biotechnology Research, University of Maryland, 3Department of Materials Science and Engineering, University of Maryland
מאמר זה מתאר גישה biofabrication: בתצהיר של גירויים, תגובה סוכרים בנוכחות אלקטרודות משוחדים ליצור סרטים ביולוגית אשר יכולה להיות פונקציונליות עם תאים או חלבונים. אנחנו מדגימים אסטרטגיה הספסל העליון לדור של סרטים כמו גם השימושים הבסיסיים ליצירת משטחים biofunctionalized אינטראקטיביים עבור מעבדה על שבב יישומים.
Other articles by Yi Cheng on PubMed
Trends in Cognitive Sciences. Jan, 2003 | Pubmed ID: 12517355
Visual recognition of objects is an impressively difficult problem that biological systems solve effortlessly. We consider two aspects of this ability. First, is the recognition of all objects accomplished by either a single system or multiple, domain-specific systems? Behavioral, neuropsychological and neuroimaging data indicate that a single system is sufficient for the recognition of all objects at all levels. Second, how does such a system 'tune' itself to the constraints imposed by recognition at different levels of specificity? Evidence indicates that the task demands and learning that arise from different forms of feedback determine which computational routines are recruited automatically in object recognition.
Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. May, 2011 | Pubmed ID: 20419494
Several trials had independently noted that patients receiving megestrol acetate had less nausea and vomiting, but this antiemetic activity of megestrol acetate has not been reported separately in the literature. Our objective was to evaluate the antiemetic ability of megestrol acetate in patients receiving chemotherapy.
Journal of Liposome Research. Sep, 2011 | Pubmed ID: 21545336
In this study, NOH (NOH = N-octadecyl-4-[(D-galactopyranosyl)oxy]-2,3,5,6-tetrahydroxy hexanamide) was enzymatically synthesized as a targeting molecule and incorporated into liposomes to prepare a liposome surface modified with galactose. Glycyrrhetinic-acid-loaded liposome (GA-LP) and glycyrrhetinic-acid-loaded liposome surface modified with galactose (NOH-GA-LP) were prepared by the ethanol-injection method. NOH-GA-LP was characterized by morphology, particle size, zeta potential, encapsulation efficiency, release in vitro, and stability. The size of spherical particles was in the range of 179-211 nm. Spherical particles exhibit a positive electrical charge (38.7 mV) and possess high encapsulation efficiency (91.3%) and show sustained release (72% over 48 hours) in vitro. This novel approach for the liposome surface modified with galactose by enzymatic synthesis is expected to provide potential application as a drug carrier for active targeted delivery to hepatocytes.
HPLC Assay and Pharmacokinetics and Tissue Distribution Study of Glycyrrhetinic Acid Liposomes Modified with Galactosylated Lipid
Journal of Liposome Research. Feb, 2012 | Pubmed ID: 22313057
The aim of this study was to evaluate the pharmacokinetics and tissue distribution of the glycyrrhetinic acid (GA) liposome modified with galactosylated lipid (NOH-GA-LP), compared with GA conventional liposome (GA-LP) and GA solution in mice. The pharmacokinetics and biodistribution of liposomal and solution formulation of GA in mice were studied after intravenous administration. Plasma and tissues were treated using liquid-liquid extraction and determined using reversed-phase high-performance liquid chromatography. Results showed that the mean residence times of NOH-GA-LP (2.99-fold) and GA-LP (2.94-fold) were higher than that of the GA solution in plasma. NOH-GA-LP produced a drug concentration in the liver that was markedly higher than that in other tissues and was approximately 2.0- and 4.8-fold of that of GA-LP and GA solution, respectively. In conclusion, the NOH-GA-LP prepared in this study is a promising sustained-release and drug-targeting system for antitumor drugs.