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In JoVE (1)
- Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering
Other Publications (4)
Articles by Yogesh Ner in JoVE
Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering
Shivanjali Joshi-Barr1, Jerome V. Karpiak2, Yogesh Ner1, Jessica H. Wen3, Adam J. Engler3, Adah Almutairi1,2
1Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 2Biomedical Sciences Program, University of California, San Diego, 3Department of Bioengineering, University of California, San Diego
Here we describe a unique strategy for creating biocompatible, layered matrices with continuous interfaces between distinct layers for tissue engineering. Such a scaffold could provide an ideal customizable environment to modulate cell behavior by various biological, chemical or mechanical cues
Published February 12, 2013. Keywords: Bioengineering, Biomedical Engineering, Tissue Engineering, Cell Culture Techniques, Tissue Culture Techniques, hydrogels, life sciences, bioengineering (general), Scaffolds, hydrogels, cell culture, polyethylene glycol, RGDS
Other articles by Yogesh Ner on PubMed
White Luminescence from Multiple-dye-doped Electrospun DNA Nanofibers by Fluorescence Resonance Energy Transfer
Angewandte Chemie (International Ed. in English). 2009 | Pubmed ID: 19504507
A DNA spin-off: Electrospinning of DNA complexes gives nanofibers with a highly ordered morphology that allows homogeneous distribution of encapsulated multiple chromophores. The emission color can be controlled by suitable choice of the donor-acceptor pair and the doping ratio. Pure white-light emission from nanofibers is demonstrated (see picture).
ACS Applied Materials & Interfaces. Oct, 2009 | Pubmed ID: 20355838
A simplified approach to constructing a composite material comprised of aligned electrospun nanofibers onto a flexible substrate consisting of a microfilament yarn is presented. The metal-coated knit patterns of the microfilament yarn play the role of the parallel electrode, required for the alignment of electrospun nanofibers. Hybrid materials with knitted textile as a support material and aligned high-surface-area nanofibers could represent ideal materials for use in the filtration, optical, and biomedical industries.
Chemical Communications (Cambridge, England). Nov, 2011 | Pubmed ID: 21998819
An efficient cascade FRET was realized in solid state DNA-CTMA thin films using a three chromophore system without any covalent attachments. The extent of energy transfer from Cm102 to SRh was studied and found to improve eight-fold using the bridging dye Pm567.
Advanced Materials (Deerfield Beach, Fla.). Mar, 2012 | Pubmed ID: 22318771
An adaptable density gradient multilayer polymerization (DGMP) method facilitates simple fabrication of complex multicompartment scaffolds with structurally continuous interfaces. Solvent density liquid-liquid phase segregation compartmentalizes varied mechanical and chemical cues independently. Bulk photopolymerization produces stratified three-dimensional and two-dimensional matrices. Cells attach to patterned adhesion peptides on biomimetic 2D substrates.