Editor’s Picks! The Future of Cancer Treatment

Nanoparticles

In this exciting Editor’s Picks collection, our Science Editor, Dr. Jaydev Upponi, offers a glimpse into the world of nanoparticles—the novel delivery system of anti-cancer therapeutics. 

Jaydev Upponi, PhD.

Jaydev Upponi, PhD.

Dr. Upponi: Currently, there is a new variety of chemotherapeutic agents available to treat cancer. These chemotherapeutic agents pose potential disadvantages, such as toxicity to normal cells and premature drug degradation owing to their poor solubility.

To overcome these limitations, scientists must solubilize and increase the amount of an anti-cancer drug at the area of concern and reduce the toxicity to normal cells. This is achieved by embedding drugs into what are called nanoparticles.

Prepared using various polymers, a variety of these novel drug delivery systems are currently being used (to name a few, there are synthetic polymers, microcapsules, cell ghosts, lipoproteins, liposome and micelles). Read more…

Green With Envy: When Your Friends All Have Jobs & You’re Still in Grad School

220px-Irish_clover

Happy St. Patrick’s Day! This is a guest post by Adam Ruben, PhD—molecular biologist, television host on the Discovery Channel’s “Outrageous Acts of Science,” and author of the book “Surviving Your Stupid, Stupid Decision to Go to Grad School.”

You thought you were so smart. You picked the lab with the brilliant, dynamic PI who’s always jetting off to conferences in faraway lands. Now, eight years later, you’re e-mailing the twelfth draft of your dissertation to an adviser you haven’t seen since last summer, hoping to receive more than an automated out-of-office message in response. Cobwebs surround your desk, your thesis committee has forgotten your name, and undergrads have begun to mistake you for a Professor Emeritus. Read more…

Editor’s Picks! The Trouble With Fieldwork

High-throughput Fluorometric Measurement of Potential Soil Extracellular Enzyme Activities

This week, associate editor, Nita Vaidya, shares 4 of her favorite videos from JoVE’s Environment section. 

Nita Vaidya

Nita Vaidya

Vaidya: Something that really gets to me about fieldwork is that it’s hard to control for things. You don’t know what the environment is going to do. I was working when hurricane sandy happened doing groundwater and surface water testing, and a bunch of our samples got messed up because the rivers flooded. It’s a good idea to standardize methods in this field since so much can go wrong. Creating a video about a method provides some control—so people can see how the method is performed and use it correctly.

 

Read more…

At Clemson, Learning Protocols With Video Proves 75% Faster

Clemson Bioprinter — JoVE's Top 5 JoVE Video Protocols

Two years ago, Clemson University principal investigator, Dr. Delphine Dean, figured out a way to make teaching a novel technique in her lab 75% more efficient. Instead of giving her students a text protocol, she published and provided them with a video protocol.  The time it took to learn the procedure dropped from 1 month to 1 week. And the video would soon make her the author of the 2nd most-viewed video in JoVE. Read more…

Chemistry Solutions: Capturing Multi-Step Syntheses With Video

51039 Miller Urey Origin of Life on Earth Experiment

Editor’s Picks! Associate editor, Emily Watershighlights four videos demonstrating JoVE’s effectiveness in communicating classic and complex Chemistry.

Emily Waters JoVE ChemistryWaters: The chemistry section launched last year, and so I wanted to highlight a range of what we have. I’ve picked a couple traditional chemistry methods and two newer techniques. I think these videos are all pretty cool, and they show the range of what JoVE videos can capture. 

Read more…

800+ Institutions Have Contributed to JoVE. How Does Yours Compare?

JoVE Contributing Institutions Map

Putting JoVE’s contributing institutions on the map.

Here’s a glimpse at an often overlooked feature of JoVE—our map of contributing institutions! We take pride in the breadth and diversity of our content and contributors, and this map visualizes the scale and range of those contributions.

As of this post, we have content from institutions in 47 U.S. states, more than 40 countries, and six continents. (Our videos have even featured footage filmed in Antarctica, although none of our contributing institutions are based there.) Read more…