Targeted Expression of GFP in the Hair Follicle Using Ex Vivo Viral Transduction
Robert M. Hoffman, Lingna Li
AntiCancer, Inc.
You must be subscribed to access this content. Please click here to subscribe or get a FREE trial.
|
0:00 Title0 1:16 Skin Histoculture and Collagenase Treatment76 3:06 Transduction of Histoculture with Virus and Visualization of Fluore186 4:42 Conclusion282
|
|
The hair follicle is a highly complex appendage of the skin containing a multiplicity of cell types. The follicle undergoes constant cycling through the life of the organism including growth and resorption with growth dependent on specific stem cells. The targeting of the follicle by genes and stem cells to change its properties, in particular, the nature of the hair shaft is, discussed. Hair follicle delivery systems are described, such as liposomes and viral vectors for gene therapy. The nature of the hair follicle stem cells is discussed, in particular, its pluripotency.
|
|
For more information on targeted expression of GFP in the hair follicle using ex vivo viral transductionplease, visit Springer Protocols.
|
|
Hoffman RM, Li L (2008). Targeted Expression of GFP in the Hair Follicle Using Ex Vivo Viral Transduction. JoVE. 13. http://www.jove.com/index/details.stp?id=708, doi: 10.3791/708
|
 |
|
| |
|
Allowed tags: i, b, u, sup, sub 
|
|
|
| | ![]() |
|
|
| | |
|
| |
| | 10/05/2008 2:05:34 AM
|
|
|  |
b.bevan responded with a statement of type: Neutral
|
|
| |
| | |
|
| | | | |
| | | | | |
Has any progress been made regarding the production of a product for the cosmetic market returning grey hair to original colouring as reported in the press some time ago? |
|
| |
| | |
| | | ![]() |
|
|
| | |
|
| |
| | 06/20/2009 3:46:28 AM
|
|
| |
jms responded with a statement of type: Neutral
|
|
| |
| | |
|
| | | | |
| | | | | |
Hair follicle is a part of the skin from where the old hairs can regrow. Electrolysis and Laser hair restoration are techniques to restore the hair on balding areas. The average growth rate of healthy hair follicles on the scalp is 400 micrometer per day. www.findhairhelp.com/electrolysis.html |
|
| |
| | |
| | | ![]() |
|
|
| | |
|
| |
| | 12/03/2009 2:41:16 AM
|
|
| |
Bipasha Bose responded with a statement of type: Question
|
|
| |
| | |
|
| | | | |
| | | | | |
Here is my question- Once we do this technique in human beings, say for suppose to modify the skin colour, how long it is going to stay with the patient? Another question- won't be the viral harmful for the patient. ?
--Many thanks,
Bipasha
|
|
| |
| | |
| | | ![]() |
|
|
| | |
|
| |
| | 05/10/2010 5:54:00 AM
|
|
| |
mr. pratik responded with a statement of type: Question
|
|
| |
| | |
|
| | | | |
| | | | | |
can we use same method for human
|
|
| |
| | |
| | | ![]() |
|
|
Mailer.URL: http://www.jove.com/index/details.stp?id=708 |
|
This article is: Free Access |
You must be logged in to track comments. |
|
My Stuff (Please log in to use) |
|
Make a SuggestionIs there a technique you would like to see published? Click the button above to make a suggestion. |
|
|
|