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Murine echocardiography and ultrasound imaging

This video demonstrates use of a rail-mounted high-frequency ultrasound probe to perform echocardiography on an anesthetized mouse. The methods describe both conventional two-dimensional and M-mode measurements of cardiac function in addition to newer, more powerful tools such as color Doppler, strain analysis, as well as general and targeted contrast imaging.

Launch Video

Published: 08/08/2010

Andrew Pistner¹
Stephen Belmonte²
Tonya Coulthard³
Burns Blaxall^{4, 2}

¹Department of Pharmacology and Physiology, University of Rochester

²Aab Cardiovascular Research Institute, University of Rochester

³Visualsonics

⁴Department of Medicine, University of Rochester

Medicine, Issue 42, echocardiography, heart, mouse, strain imaging, high frequency ultrasound, contrast imaging

Assessment of Ultrasonic Vocalizations During Drug Self-administration in Rats

Drug self-administration and ultrasonic vocalizations (USV) are used as behavioral assessments in animal research, but rarely in combination. The purpose of this article is to describe the advantages of recording USVs during drug self-administration procedures to assess affective responses to drug experience.

Launch Video

Published: 07/22/2010

Esther Y. Maier^{1, 2}
Sean T. Ma³
Allison Ahrens^{2, 4}
Timothy J. Schallert^{2, 4, 5}
Christine L. Duvauchelle^{1, 2, 4}

¹College of Pharmacy, Division of Pharmacology and Toxicology, University of Texas at Austin

²The Waggoner Center of Addiction and Alcohol Research, University of Texas at Austin

³Department of Psychology, University of Michigan

⁴Institute for Neuroscience, University of Texas at Austin

⁵Department of Psychology, University of Texas at Austin

JoVE Neuroscience, Issue 41, ultrasound, behavior, self-administration, emotionality, anticipation, reward

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

High frequency Doppler ultrasound is a novel technology for assessing regional myocardial function. This work presents first evidence demonstrating applicability of this versatile imaging platform for the repeated measure of myocardial strain, dp/dt, and mitral regurgitation in the ischemia-reperfused (IR) murine heart.

Launch Video

Published: 07/09/2010

Surya C. Gnyawali^{1, 2}
Sashwati Roy^{1, 2}
Jason Driggs^{1, 2}
Savita Khanna^{1, 2}
Thomas Ryan^{3, 2}
Chandan K. Sen²

¹Department of Surgery, The Ohio State University

²Heart and Lung Research Institute, The Ohio State University

³Department of Cardiovascular Medicine, The Ohio State University

JoVE Medicine, Issue 41, ischemia-reperfused murine heart, high frequency ultrasound, heart contractility (dP/dt), mitral regurgitation

Transthoracic Echocardiography in Mice

Transthoracic echocardiography offers a noninvasive method for the evaluation of cardiac function in mice. A combination of ultrasound and Doppler imaging modalities can be used to obtain dimensional measurements of the heart and intracardiac blood flow, which together provide an assessment of cardiac systolic and diastolic performance.

Launch Video

Published: 05/28/2010

Jonathan L. Respress¹
Xander H.T. Wehrens^{1, 2}

¹Department of Molecular Physiology and Biophysics, Baylor College of Medicine

²The Margaret M. and Albert B. Alkek Department of Medicine, Baylor College of Medicine

JoVE Medicine, Issue 39, Echocardiography, pulse wave Doppler, tissue Doppler imaging, ultrasound

Page:1

Total: 4 articles.

Search results for 9/10/2010 9:48:36 AM

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Journal of Visualized Experiments (JoVE) is an online research journal employing visualization to increase reproducibility and transparency in biological sciences.

ISSN 1940-087X

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