Journal of Visualized Experiments

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Video Articles

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This video demonstrates use of a rail-mounted high-frequency ultrasound probe to perform echocardiography on an anesthetized mouse. The methods describe both conventional two-dimensional and M-mode measurements of cardiac function in addition to newer, more powerful tools such as color Doppler, strain analysis, as well as general and targeted contrast imaging.
Launch Video

    Published: 08/08/2010

Andrew Pistner1
Stephen Belmonte2
Tonya Coulthard3
Burns Blaxall4, 2

1Department of Pharmacology and Physiology, University of Rochester

2Aab Cardiovascular Research Institute, University of Rochester

3Visualsonics

4Department of Medicine, University of Rochester

 

Drug self-administration and ultrasonic vocalizations (USV) are used as behavioral assessments in animal research, but rarely in combination. The purpose of this article is to describe the advantages of recording USVs during drug self-administration procedures to assess affective responses to drug experience.
Launch Video

    Published: 07/22/2010

Esther Y. Maier1, 2
Sean T. Ma3
Allison Ahrens2, 4
Timothy J. Schallert2, 4, 5
Christine L. Duvauchelle1, 2, 4

1College of Pharmacy, Division of Pharmacology and Toxicology, University of Texas at Austin

2The Waggoner Center of Addiction and Alcohol Research, University of Texas at Austin

3Department of Psychology, University of Michigan

4Institute for Neuroscience, University of Texas at Austin

5Department of Psychology, University of Texas at Austin

 

High frequency Doppler ultrasound is a novel technology for assessing regional myocardial function. This work presents first evidence demonstrating applicability of this versatile imaging platform for the repeated measure of myocardial strain, dp/dt, and mitral regurgitation in the ischemia-reperfused (IR) murine heart.
Launch Video

    Published: 07/09/2010

Surya C. Gnyawali1, 2
Sashwati Roy1, 2
Jason Driggs1, 2
Savita Khanna1, 2
Thomas Ryan3, 2
Chandan K. Sen2

1Department of Surgery, The Ohio State University

2Heart and Lung Research Institute, The Ohio State University

3Department of Cardiovascular Medicine, The Ohio State University

 

Transthoracic echocardiography offers a noninvasive method for the evaluation of cardiac function in mice. A combination of ultrasound and Doppler imaging modalities can be used to obtain dimensional measurements of the heart and intracardiac blood flow, which together provide an assessment of cardiac systolic and diastolic performance.
Launch Video

    Published: 05/28/2010

Jonathan L. Respress1
Xander H.T. Wehrens1, 2

1Department of Molecular Physiology and Biophysics, Baylor College of Medicine

2The Margaret M. and Albert B. Alkek Department of Medicine, Baylor College of Medicine

 

 

Page:1 

 

Total: 4 articles.

 

Search results for 9/10/2010 9:48:36 AM

 

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Journal of Visualized Experiments (JoVE) is an online research journal employing visualization to increase reproducibility and transparency in biological sciences.

 

ISSN 1940-087X

 

 

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