Journal of Visualized Experiments (JoVE) is a video journal for biological research. |
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07/17/2010
Simon Rajendran1, Slawomir Salwa1, Xuefeng Gao2, Sabin Tabirca2, Deirdre O'Hanlon3, Gerald C. O'Sullivan1, Mark Tangney1
1Cork Cancer Research Centre, Mercy University Hospital and Leslie C. Quick Jnr. Laboratory, University College Cork, 2Department of Computer Science, University College Cork, 3South Infirmary Victoria University Hospital
This article describes a procedure for the induction of orthotopic bioluminescent liver tumours in mice, and subsequent analysis of tumour growth confined to the liver using live whole body luminescence imaging.
07/09/2010
Surya C. Gnyawali1, 2, Sashwati Roy1, 2, Jason Driggs1, 2, Savita Khanna1, 2, Thomas Ryan3, 2, Chandan K. Sen2
1Department of Surgery, The Ohio State University, 2Heart and Lung Research Institute, The Ohio State University, 3Department of Cardiovascular Medicine, The Ohio State University
High frequency Doppler ultrasound is a novel technology for assessing regional myocardial function. This work presents first evidence demonstrating applicability of this versatile imaging platform for the repeated measure of myocardial strain, dp/dt, and mitral regurgitation in the ischemia-reperfused (IR) murine heart.
06/22/2010
Douglas Nam1, Chih-Wen Ni2, Amir Rezvan1, Jin Suo2, Klaudia Budzyn1, Alexander Llanos1, David G. Harrison1, Don P. Giddens2, Hanjoong Jo1, 2, 3
1Department of Medicine, Division of Cardiology, Emory University, 2Coulter Department of Biomedical Engineering, Georgia Tech and Emory University, 3Department of Bioinspired Science, Ewha Womans University
This describes a partial carotid ligation surgery, which causes disturbed flow conditions and subsequent atherosclerosis development (in two weeks) with intraplaque neo-vascularization (in four weeks) in the mouse common carotid artery. We also describe a novel method of RNA isolation from the carotid intima, providing high purity endothelial RNA.
06/21/2010
Glenn H. Raup1, Jeff King2, Romana J. Hughes2, Natasha Faidley2
1Harris College of Nursing and Health Sciences, 2Koehler Center for Teaching Excellence, Texas Christian University
The structure and process for measuring student learning outcomes through customizable assessment rubrics is discussed and applied to a doctoral nursing education program.
06/05/2010
Bruno Gualano1, 2, Carlos Ugrinowitsch1, Manoel Neves Jr.2, Fernanda R. Lima2, Ana Lúcia S. Pinto2, Gilberto Laurentino1, Valmor A.A. Tricoli1, Antonio H. Lancha Jr.1, Hamilton Roschel1, 2
1School of Physical Education and Sport, University of São Paulo, 2Division of Rheumatology, School of Medicine, University of São Paulo
The present article presents the details pertaining to the application of resistance training associated to vascular occlusion in IBM patients.
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