Max Planck Institute of Biophysics View Institution's Website 2 articles published in JoVE Biology Visualization of ATP Synthase Dimers in Mitochondria by Electron Cryo-tomography Karen M. Davies1, Bertram Daum1, Vicki A. M. Gold1, Alexander W. Mühleip1, Tobias Brandt1, Thorsten B. Blum1, Deryck J. Mills1, Werner Kühlbrandt1 1Department of Structural Biology, Max Planck Institute of Biophysics We present a protocol of how to collect and process electron cryo-tomograms of whole mitochondria. The technique provides detailed insights into the structure, function, and organization of large membrane protein complexes in native biological membranes. Biology Introduction to Solid Supported Membrane Based Electrophysiology Andre Bazzone1, Wagner Steuer Costa2, Markus Braner1, Octavian Călinescu1, Lina Hatahet1, Klaus Fendler1 1Department of Biophysical Chemistry, Max Planck Institute of Biophysics, 2Buchmann Institute for Molecular Life Sciences, Goethe University Frankfurt Here we present an electrophysiological method based on solid supported membranes with focus on its applications for the characterization of electrogenic membrane transporters.