London Health Science Centre View Institution's Website 2 articles published in JoVE Medicine Evaluation of Nanoparticle Uptake in Tumors in Real Time Using Intravital Imaging Choi-Fong Cho1, Amber Ablack2, Hon-Sing Leong2, Andries Zijlstra3, John Lewis2,4 1Department of Medical Biophysics, University of Western Ontario, 2London Regional Cancer Program, London Health Science Centre, 3Department of Pathology, Vanderbilt University, 4Translational Prostate Cancer Research Group, London Health Science Centre We present a novel approach to quantify nanoparticle localization in the vasculature of human xenografted tumors using dynamic, real-time intravital imaging in an avian embryo model. Medicine Quantitative Analysis of Cancer Metastasis using an Avian Embryo Model Trenis D. Palmer1, John Lewis2, Andries Zijlstra1 1Department of Pathology, Vanderbilt University, 2Departments of Oncology, Surgery and Medical Biophysics, London Regional cancer program Using quantitative PCR, we demonstrate how the well-established chick CAM model can be used to quantitatively analyze the metastasis of human tumor cells to distant organs.
