LoneStar Heart, Inc. View Institution's Website 1 article published in JoVE Medicine Reduction in Left Ventricular Wall Stress and Improvement in Function in Failing Hearts using Algisyl-LVR Lik Chuan Lee1, Zhang Zhihong1, Andrew Hinson2, Julius M. Guccione1 1Department of Surgery, UCSF/VA Medical Center, 2Clinical & Regulatory, LoneStar Heart, Inc. This article describes procedures for implanting a novel hydrogel in failing hearts and quantifying its effect on left ventricular wall stress and function. These procedures have been successfully applied in dogs and humans.