New Jersey Institute of Technology View Institution's Website 7 articles published in JoVE Bioengineering Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes Sebastian N. Fine1, Yi Guo1,2, Henry Talasan1, Stephen LeStrange1, Chang Yaramothu1,3, Tara L. Alvarez1 1Department of Biomedical Engineering, New Jersey Institute of Technology, 2Neural Automations Ltd., 3School of Applied Engineering and Technology, New Jersey Institute of Technology VisualEyes2020 (VE2020) is a custom scripting language that presents, records, and synchronizes visual eye movement stimuli. VE2020 provides stimuli for conjugate eye movements (saccades and smooth pursuit), disconjugate eye movements (vergence), accommodation, and combinations of each. Two analysis programs unify the data processing from the eye tracking and accommodation recording systems. Chemistry Probing Surface Electrochemical Activity of Nanomaterials using a Hybrid Atomic Force Microscope-Scanning Electrochemical Microscope (AFM-SECM) Xiaonan Shi1, Qingquan Ma1, Taha Marhaba1, Wen Zhang1 1Department of Civil and Environmental Engineering, New Jersey Institute of Technology Atomic force microscopy (AFM) combined with scanning electrochemical microscopy (SECM), namely, AFM-SECM, can be used to simultaneously acquire high-resolution topographical and electrochemical information on material surfaces at nanoscale. Such information is critical to understanding heterogeneous properties (e.g., reactivity, defects, and reaction sites) on local surfaces of nanomaterials, electrodes and biomaterials. Medicine Transplantation of Schwann Cells Inside PVDF-TrFE Conduits to Bridge Transected Rat Spinal Cord Stumps to Promote Axon Regeneration Across the Gap Yee-Shuan Lee1, Siliang Wu2, Treena Livingston Arinzeh3, Mary Bartlett Bunge1,4,5 1The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, 2Department of Materials Science and Engineering, New Jersey Institute of Technology, 3Department of Biomedical Engineering, New Jersey Institute of Technology, 4Department of Cell Biology, University of Miami Miller School of Medicine, 5Department of Neurological Surgery, University of Miami Miller School of Medicine This article describes a technique to insert a hollow conduit between the spinal cord stumps after complete transection and fill with Schwann cells (SCs) and injectable basement membrane matrix in order to bridge and promote axon regeneration across the gap. Bioengineering A Versatile Method of Patterning Proteins and Cells Anil B. Shrirao*1, Frank H. Kung*2, Derek Yip3, Bonnie L. Firestein2, Cheul H, Cho3, Ellen Townes-Anderson4 1Department of Biomedical Engineering, Rutgers University, 2Department of Cell Biology and Neuroscience, Rutgers University, 3Department of Biomedical Engineering, New Jersey Institute of Technology, 4Department of Pharmacology, Physiology, and Neuroscience, Rutgers New Jersey Medical School This report describes a simple, easy to perform technique, using low pressure vacuum, to fill microfluidic channels with cells and substrates for biological research. Bioengineering Culturing Mouse Cardiac Valves in the Miniature Tissue Culture System Boudewijn P.T. Kruithof1, Samuel C. Lieber2, Marianna Kruithof-de Julio3, Vincian Gaussin4, Marie José Goumans1 1Department of Molecular Cell Biology, Leiden University Medical Center, 2Department of Engineering Technology, New Jersey Institute of Technology, 3Department of Urology, Leiden University Medical Center, 4Cardiovascular Research Institute, Department of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School Here, we present an ex vivo flow model in which murine cardiac valves can be cultured allowing the study of the biology of the valve. Bioengineering Axon Stretch Growth: The Mechanotransduction of Neuronal Growth Joseph R. Loverde1,2, Rosa E. Tolentino1,2, Bryan J. Pfister1 1Departments of Biomedical Engineering, New Jersey Institute of Technology, 2Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey A unique tissue engineering method was developed to elongate numerous nerve fibers in culture by recapitulating axon stretch growth; a form of nervous system growth whereby nerves elongate in conjunction with growth of the enlarging body. Neuroscience VisualEyes: A Modular Software System for Oculomotor Experimentation Yi Guo1, Eun H. Kim1, Tara L. Alvarez1 1Department of Biomedical Engineering, New Jersey Institute of Technology Neural control and cognitive processes can be studied through eye movements. The VisualEyes software allows an operator to program stimuli on two computer screens independently using a simple, custom scripting language. The system can stimulate tandem eye movements (saccades and smooth pursuit) or opposing eye movements (vergence) or any combination.
