Quantifying Cognitive Decrements Caused by Cranial Radiotherapy

JoVE 3108 10/18/2011

Lori- Ann Christie, Munjal M. Acharya, Charles L. Limoli

Department of Radiation Oncology, University of California Irvine

Cognitive impairment resulting from the radiotherapeutic management of brain tumors represents a clinically intractable condition that adversely impacts quality of life. The capability to critically evaluate potential interventions for ameliorating radiation-induced cognitive decrements ultimately depends on the capability to undertake rigorous quantitative assessments of cognition.

October 2011: This Month in JoVE

JoVE 3957 10/01/2011

Aaron Kolski-Andreaco

Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions

JoVE 2670 5/23/2011

Vera Brümmer¹, Stefan Schneider¹, Tobias Vogt¹, Heiko Strüder¹, Heather Carnahan², Christopher D. Askew³, Roland Csuhaj⁴

¹Institute of Movement and Neurosciences, German Sport University Cologne, ²Deptartment of Surgical Skills, University of Toronto, ³School of Human Movement Studies, Institute of Health and Biomedical Innovation, Queensland University of Technology, ⁴Brain Products GmbH, Scientific Support, Gilching, Germany

The effect of weightlessness and hypergravity on both hemodynamic and electrophysiological processes in the brain is going to be followed during parabolic flight by EEG and NIRS techniques. A feasibility study of a more complex experiment, which is planned to carry out during medium- and long-term space flight.

High Density Event-related Potential Data Acquisition in Cognitive Neuroscience

JoVE 1945 4/16/2010

Scott D. Slotnick

Department of Psychology, Boston College

Event-related potential (ERP) recording is under utilized in Cognitive Neuroscience because data acquisition techniques are not readily available and this method often has poor spatial resolution. To foster the increased use of ERPs in Cognitive Neuroscience, the present article details key techniques involved in high density ERP data acquisition.

Making Sense of Listening: The IMAP Test Battery

JoVE 2139 10/11/2010

Johanna G. Barry*¹, Melanie A. Ferguson*², David R. Moore*¹

¹MRC Institute of Hearing Research, ²NIHR, National Biomedical Research Unit in Hearing

A test battery (IMAP) for performing an in-depth assessment of auditory and cognitive abilities contributing to listening skills is described. It is quick to administer, child-friendly and free from linguistic confounds. Stimulus generation and protocol management are controlled via a software platform (IHR-STAR) to ensure replicable procedures.

The use of Biofeedback in Clinical Virtual Reality: The INTREPID Project

JoVE 1554 11/12/2009

Claudia Repetto¹, Alessandra Gorini¹, Cinzia Vigna¹, Davide Algeri¹, Federica Pallavicini¹, Giuseppe Riva^1,2

¹Applied Technology for Neuro-Psychology Lab, Istituto Auxologico Italiano, ²Psychology Department, Università Cattolica del Sacro Cuore

The Project on Virtual Reality Intelligent Multi-sensor System for the Treatment of Anxiety-related Disorders (INTREPID) is aimed at developing a multi-sensor context-aware virtual reality system for the treatment of anxiety-related disorders.

Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care

JoVE 2342 2/16/2011

Laura S. Lorenz*^1,2, Jon A. Chilingerian*²

¹Institute for Behavioral Health, Brandeis University, ²Heller School for Social Policy and Management, Brandeis University

This paper illustrates an innovative visual approach (photovoice or photo-elicitation) to achieve fair process in clinical care for patients living with chronic health conditions, illuminate gaps in clinical knowledge, forge better therapeutic relationships, and identify patient-centered goals and possibilities for healing.

Measurement Of Neuromagnetic Brain Function In Pre-school Children With Custom Sized MEG

JoVE 1693 2/19/2010

Graciela Tesan, Blake W. Johnson, Melanie Reid, Rosalind Thornton, Stephen Crain

Macquarie Centre for Cognitive Science, Macquarie University

The advent of MEG systems sized for young children opens important new opportunities to study brain development. The new system, together with a protocol that aligns experimental requirements with the capacities of children, can be used to study cognitive and language processes in healthy, awake children aged three to six.

Stem Cell Transplantation Strategies for the Restoration of Cognitive Dysfunction Caused by Cranial Radiotherapy

JoVE 3107 10/18/2011

Munjal M. Acharya*, Dante E. Roa*, Omar Bosch, Mary L. Lan*, Charles L. Limoli

Department of Radiation Oncology, University of California Irvine

Brain tumor patients routinely undergo cranial radiotherapy, and while beneficial, this treatment often results in debilitating cognitive dysfunction. This serious unresolved problem has at present, no clinical recourse, and has driven our efforts to devise stem cell based therapies for the recovery of radiation-induced cognitive decrements.

Assessment of Motor Balance and Coordination in Mice using the Balance Beam

JoVE 2376 3/10/2011

Tinh N. Luong*, Holly J. Carlisle*, Amber Southwell, Paul H. Patterson

Department of Biology, California Institute of Technology

Deficits in fine motor coordination can be assessed with the balance beam test. Performance on the beam is quantified by the speed at which the beam is traversed and the number of times the mouse slips on the beam.