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Conscious Sedation: A drug-induced depression of consciousness during which patients respond purposefully to verbal commands, either alone or accompanied by light tactile stimulation. No interventions are required to maintain a patent airway. (From: American Society of Anesthesiologists Practice Guidelines)
 JoVE Medicine

Bronchoalveolar Lavage (BAL) for Research; Obtaining Adequate Sample Yield

1Biomedical Research Centre in Microbial Diseases, National Institute for Health Research, 2Respiratory Infection Group, Royal Liverpool and Broadgreen University Hospital Trust, 3Respiratory Infection Group, Liverpool School of Tropical Medicine, 4Institute of Infection and Global Health, University of Liverpool, 5Comprehensive Local Research Network, Royal Liverpool and Broadgreen University Hospital Trust, 6Department of Respiratory Research, University Hospital Aintree


JoVE 4345

 JoVE Medicine

High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart

1Department of Surgery, The Ohio State University, 2Heart and Lung Research Institute, The Ohio State University, 3Department of Cardiovascular Medicine, The Ohio State University


JoVE 1781

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 JoVE Behavior

Conscious and Non-conscious Representations of Emotional Faces in Asperger's Syndrome

1Institute of Statistical Science, Academia Sinica, 2Max Planck Institute for Human Cognitive and Brain Sciences, 3Department of Psychology, Fo Guang University, 4Department of Electrical Engineering, Fu Jen Catholic University, 5State Research Institute of Physiology and Basic Medicine, 6Novosibirsk State University, 7Imaging Research Center, Taipei Medical University


JoVE 53962

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 JoVE Behavior

Studying Food Reward and Motivation in Humans

1Department of Psychiatry, University of Cambridge, 2Metabolic Research Laboratories, Wellcome Trust-MRC Institute of Metabolic Science, University of Cambridge, 3Cambridgeshire & Peterborough NHS Foundation Trust, University of Cambridge, 4West Anglia Comprehensive Local Research Network, Addenbrooke's Hospital


JoVE 51281

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 Science Education: Essentials of Sensation and Perception

Object Substitution Masking

JoVE Science Education

Source: Laboratory of Jonathan Flombaum—Johns Hopkins University

Visual masking is a term used by perceptual scientists to refer to a wide range of phenomena in which in an image is presented but not perceived by an observer because of the presentation of a second image. There are several different kinds of masking, many of them relatively intuitive and unsurprising. But one surprising and important type of masking is called Object Substitution Masking. It has been a focus of research in vision science since it was discovered, relatively recently, around 1997 by Enns and Di Lollo.1 This video will demonstrate standard procedures for how to conduct an object substitution experiment, how to analyze the results, and it will also explain the hypothesized causes for this unusual form of masking.

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 JoVE Cancer Research

Operating Procedures of the Electrochemotherapy for Treatment of Tumor in Dogs and Cats

1Clinic for Surgery and Small Animals, Veterinary Faculty, University of Ljubljana, 2Department of Experimental Oncology, Institute of Oncology Ljubljana, 3Faculty of Health Sciences, University of Primorska, 4IPBS (Institut de Pharmacologie et de Biologie Structurale), CNRS, 5IPBS (Institut de Pharmacologie et de Biologie Structurale), Université de Toulouse


JoVE 54760

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 Science Education: Essentials of Lab Animal Research

Compound Administration III

JoVE Science Education

Source: Kay Stewart, RVT, RLATG, CMAR; Valerie A. Schroeder, RVT, RLATG. University of Notre Dame, IN

There are many commonly used routes for compound administration in laboratory mice and rats. However, certain protocols may require the use of less commonly used routes, including intradermal, intranasal, and intracranial injections. Specialized training is essential for these procedures to be performed successfully. Justification for these routes may need to be provided to gain Institutional Animal Care and Use Committee (IACUC) approval.

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 Science Education: Essentials of Cognitive Psychology

Binocular Rivalry

JoVE Science Education

Source: Laboratory of Jonathan Flombaum—Johns Hopkins University

Why do people have two forward-facing eyes? By presenting the brain with two ever so slightly different images it becomes possible to comprehend visual problems that are far more difficult to process through a single eye. Chief among these is the problem of 3-D perception, seeing the world in three dimensions, despite retinal inputs in only two dimensions. What happens if each eye receives two completely different images? That does not happen in nature, to be sure, but it can be contrived in the laboratory in a set-up called binocular rivalry. Binocular rivalry is a common laboratory paradigm for investigating the ways that the brain integrates information from two eyes, and in recent years, the mechanisms responsible for producing conscious experience.

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 JoVE Medicine

Development of an Algorithm to Perform a Comprehensive Study of Autonomic Dysreflexia in Animals with High Spinal Cord Injury Using a Telemetry Device

1International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British Columbia, 2Department of Medicine, Division of Physical Medicine and Rehabilitation, University of British Columbia, GF Strong Rehabilitation Centre


JoVE 52809

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