The Journal of Visualized Experiments (JoVE) is a peer reviewed, PubMed-indexed video journal. Our mission is to increase the productivity of scientific research.

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In vitro Mesothelial Clearance Assay that Models the Early Steps of Ovarian Cancer Metastasis


JoVE 3888 2/17/2012

Department of Cell Biology, Harvard Medical School

The mesothelial clearance assay described here takes advantage of fluorescently labeled cells and time-lapse video microscopy to visualize and quantitatively measure the interactions of ovarian cancer multicellular spheroids and mesothelial cell monolayers. This assay models the early steps of ovarian cancer metastasis.

 

February 2012: This Month in JoVE


JoVE 4258 2/01/2012

 

Mouse Embryonic Lung Culture, A System to Evaluate the Molecular Mechanisms of Branching


JoVE 2035 6/30/2010

Saban Research Institute, Childrens Hospital Los Angeles

Early embryonic lung organ culture is a very useful system to study epithelial-mesenchymal interactions. Both epithelial and mesenchymal morphogenesis proceeds under specific conditions that can be readily manipulated in this system.

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