Myositis:
Inflammation of a muscle or muscle tissue.
JoVE Clinical and Translational Medicine
Vascular Occlusion Training for Inclusion Body Myositis: A Novel Therapeutic Approach
1School of Physical Education and Sport, University of São Paulo, 2Division of Rheumatology, School of Medicine, University of São Paulo
The present article presents the details pertaining to the application of resistance training associated to vascular occlusion in IBM patients.
JoVE Immunology and Infection
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Department of Pediatrics, Cedars-Sinai Medical Center
Murine skin and soft tissue infection model is utilized for assessing the virulence function of methicillin resistant Staphylococcus aureus (MRSA) and the host immunological responses. Here, we presented a subcutaneous infection model for skin and soft tissue infection.
JoVE Neuroscience
A Caenorhabditis elegans Model System for Amylopathy Study
We describe methods to study aspects of amylopathies in the worm C. elegans. We show how to construct worms expressing human Aβ42 in neurons and how to test their function in behavioral assays. We further show how to obtain primary neuronal cultures that can be used for pharmacological testing.
JoVE Neuroscience
Assaying β-amyloid Toxicity using a Transgenic C. elegans Model
1Institute for Behavioral Genetics, University of Colorado, 2Integrative Physiology, University of Colorado
The intensely studied nematode worm Caenorhabditis elegans can be transgenically engineered to express the human β-amyloid peptide (Aβ). Induced expression of Aβ in C. elegans muscle leads to a rapid, reproducible paralysis phenotype that can be used to monitor treatments that modulate Aβ toxicity.
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