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Pain, Referred: A type of pain that is perceived in an area away from the site where the pain arises, such as facial pain caused by lesion of the Vagus nerve, or throat problem generating referred pain in the ear.
 JoVE In-Press

A Protocol of Manual Tests to Measure Sensation and Pain in Humans

1Physical Therapy, Chronic Pain Research Consortium, Duquesne University, 2Biological Sciences, Chronic Pain Research Consortium, Duquesne University, 3Chronic Pain Research Consortium, Duquesne University, 4Psychology, Chronic Pain Research Consortium, Duquesne University, 5Occupational Therapy, Chronic Pain Research Consortium, Duquesne University

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JoVE 54130

 Science Education: Essentials of Physical Examinations II

Abdominal Exam IV: Acute Abdominal Pain Assessment

JoVE Science Education

Source: Joseph Donroe, MD, Internal Medicine and Pediatrics, Yale School of Medicine, New Haven, CT

Abdominal pain is a frequent presenting concern in both the emergency department and the office setting. Acute abdominal pain is defined as pain lasting less than seven days, while an acute abdomen refers to the abrupt onset of severe abdominal pain with features suggesting a surgically intervenable process. The differential diagnosis of acute abdominal pain is broad; thus, clinicians must have a systematic method of examination guided by a careful history, remembering that pathology outside of the abdomen can also cause abdominal pain, including pulmonary, cardiac, rectal, and genital disorders. Terminology for describing the location of abdominal tenderness includes the right and left upper and lower quadrants, and the epigastric, umbilical, and hypogastric regions (Figures 1, 2). Thorough examination requires an organized approach involving inspection, auscultation, percussion, and palpation, with each maneuver performed purposefully and with a clear mental representation of the anatomy. Rather than palpating randomly across the abdomen, begin palpating remotely from the site of tenderness, moving systematically toward the tender region, and thi

 JoVE Behavior

Method for Simultaneous fMRI/EEG Data Collection during a Focused Attention Suggestion for Differential Thermal Sensation

1Neuropsychiatric Institute, University of California, Los Angeles, 2Laboratory of Neuroimaging Technology, University of California, Los Angeles, 3Yale School of Medicine, 4Korean Basic Science Institute


JoVE 3298

 JoVE Neuroscience

Flat Mount Imaging of Mouse Skin and Its Application to the Analysis of Hair Follicle Patterning and Sensory Axon Morphology

1Department of Molecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, 2Department of Neuroscience, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, 3Department of Ophthalmology, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine


JoVE 51749

 JoVE Medicine

Performing and Processing FNA of Anterior Fat Pad for Amyloid

1Department of Pathology, Medical College of Wisconsin, 2Current Address: Department of Pathology, Wayne State University School of Medicine Detroit Medical Center, 3Department of Neurology, Medical College of Wisconsin, 4Department of Medicine, Medical College of Wisconsin, 5Division of Neoplastic Diseases and Related Disorders, Medical College of Wisconsin


JoVE 1747

 JoVE Cancer Research

Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones

1Department of Surgery, The University of Chicago, 2Department of Radiation and Cellular Oncology and Ludwig Center for Metastasis Research, The University of Chicago


JoVE 54657

 JoVE Medicine

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

1Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran, 2Department of Endocrinology & Female Infertility, Reproductive Biomedicine Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran


JoVE 4372

 JoVE Bioengineering

The Arteriovenous (AV) Loop in a Small Animal Model to Study Angiogenesis and Vascularized Tissue Engineering

1Department of Plastic and Hand Surgery and Laboratory for Tissue Engineering and Regenerative Medicine, University Hospital of Erlangen, Friedrich-Alexander University of Erlangen-Nürnberg (FAU), 2Genetic Engineering and Biotechnology Institute for Postgraduate Studies, Baghdad University, 3Department of Plastic, Hand and Microsurgery, Sana Klinikum Hof GmbH


JoVE 54676

 Science Education: Essentials of Sensation and Perception

The Rubber Hand Illusion

JoVE Science Education

Source: Laboratory of Jonathan Flombaum—Johns Hopkins University

Reaching for objects, walking without hitting obstacles, landing on a chair as you sit (instead of falling to the floor), these and all our physical actions depend on an ability to perceive our own bodies in space, to know where our limbs are relative to one another and relative to the rest of the world. One way that the human brain encodes this information is called proprioception, the brain relies on its own control and feedback signals to keep track of limbs. Along with proprioceptive inputs, the human brain incorporates vision, touch, and even sound in order to represent the parts of the body in space. How does it combine all this information? In 1998, Botvinick and Cohen described a striking illusion, called the Rubber Hand Illusion, that has been used to investigate how the human brain integrates sensory and proprioceptive inputs to represent the body in space.1 This video will demonstrate how to induce the Rubber Hand Illusion and it will describe how it has been used by subsequent studies.

 JoVE Medicine

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

1Department of Radiation Oncology, University of Toronto, 2Department of Physics, Ryerson University, 3Department of Medical Biophysics, University of Toronto, 4Ontario Cancer Institute / Campbell Family Institute for Cancer Research


JoVE 53573

 JoVE Neuroscience

Local and Global Methods of Assessing Thermal Nociception in Drosophila Larvae

1Department of Biochemistry and Molecular Biology, The University of Texas MD Anderson Cancer Center, 2Scholars Academy/MARC Scholar, University of Houston-Downtown, 3Genes and Development Graduate Program, University of Texas Graduate School of Biomedical Sciences, 4Neuroscience Graduate Program, University of Texas Graduate School of Biomedical Sciences


JoVE 3837

 Science Education: Essentials of Neuropsychology

Motor Maps

JoVE Science Education

Source: Laboratories of Jonas T. Kaplan and Sarah I. Gimbel—University of Southern California

One principle of brain organization is the topographic mapping of information. Especially in sensory and motor cortices, adjacent regions of the brain tend to represent information from adjacent parts of the body, resulting in maps of the body expressed on the surface of the brain. The primary sensory and motor maps in the brain surround a prominent sulcus known as the central sulcus. The cortex anterior to the central sulcus is known as the precentral gyrus and contains the primary motor cortex, while the cortex posterior to the central sulcus is known as the postcentral gyrus and contains the primary sensory cortex (Figure 1). Figure 1: Sensory and motor maps around the central sulcus. The primary motor cortex, which contains a motor map of the body's effectors, is anterior to the central sulcus, in the precentral gyrus of the frontal lobe. The primary somesthetic (sensory) cortex, which receives touch, pain, and temperature information from the external parts of the body, is located posterior to the central sulcus, in the postcentral gyrus of the parietal lobe.

 JoVE Immunology and Infection

Measuring Local Anaphylaxis in Mice

1Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences


JoVE 52005

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