Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

JoVE 227 7/04/2007

John Marshall, Koji Morikawa, Nicholas Manoukis, Charles Taylor

Department of Ecology and Evolutionary Biology, University of California, Los Angeles

Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy. Insight is given into how computational models can provide information on the population dynamics of mosquitoes and the spread of transposable elements through A. gambiae subspecies. The ethical considerations of releasing genetically modified mosquitoes into the wild are discussed.