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Journal / Biology / Gebrekkige PMS2, ERCC1, Ku86, CcOI in Field…
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Gebrekkige PMS2, ERCC1, Ku86, CcOI in Field Gebreken Tijdens Progressie naar Colon Cancer
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Gebrekkige PMS2, ERCC1, Ku86, CcOI in Field Gebreken Tijdens Progressie naar Colon Cancer

Article DOI: 10.3791/1931-v • 28:16 min • July 28th, 2010
July 28th, 2010 •
1, 1, 1, 1, 1, 1, 2,3, 1,4, 3, 5, 5, 5, 1
1Department of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson, 2Southern Arizona Veterans Affairs Health Care System, Tucson, AZ, 3Department of Surgery, College of Medicine, University of Arizona, Tucson, 4Biomedical Diagnostics and Research, Tucson, AZ, 5Department of Medicine, College of Medicine, University of Arizona, Tucson

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Verminderd / afwezige uitdrukking van PMS2 en / of ERCC1 in hele crypten is een frequent geval binnen 10 cm aan elke kant van colon adenocarcinomen, waarschijnlijk de basis van een gezichtsveld met een hoge veranderlijkheid en de progressie van kanker. Deficiëntie in Ku86 of CcOI is veel minder frequent in deze veld gebreken.

Tags

Cellular Biology DNA Repair Apoptosis Field Defect Colon Cancer PMS2 ERCC1 cytochroom c oxidase subeenheid I Ku86 immunohistochemie Kreeft resectie
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