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 JoVE Biology

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

1, 1, 1, 1

1Department of Ecology and Evolutionary Biology, University of California, Los Angeles

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    Summary

    Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy. Insight is given into how computational models can provide information on the population dynamics of mosquitoes and the spread of transposable elements through A. gambiae subspecies. The ethical considerations of releasing genetically modified mosquitoes into the wild are discussed.

    Date Published: 7/04/2007, Issue 5; doi: 10.3791/227

    Cite this Article

    Marshall, J., Morikawa, K., Manoukis, N., Taylor, C. Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling. J. Vis. Exp. (5), e227, doi:10.3791/227 (2007).

    Abstract

    Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy. Insight is given into how computational models can provide information on the population dynamics of mosquitoes and the spread of transposable elements through A. gambiae subspecies. The ethical considerations of releasing genetically modified mosquitoes into the wild are discussed.

    Disclosures

    The authors have nothing to disclose.

    Comments

    1 Comment

    Hi, I am a french student in Biotechnology at the University of Strasbourg. In order to obtain my 5 years diploma we have a project to carry out. We have to create a fictive start up in Biotechnology. Our aim is to produce mosquitŒs resistant to malaria. In order to do this we  would like to perform mathematical modeling. I would like to know if the program used in your experiment could be used in our "fictive start up". Is it a free or could you provide it to us  in our fictive start up ?   Thanks for your time and consideration   Aurore-Cécile Valfort      
    Reply

    Posted by: AnonymousDecember 7, 2008, 8:50 AM

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