Building a Better Mosquito: Identifying the Genes Enabling Malaria and Dengue Fever Resistance in A. gambiae and A. aegypti Mosquitoes

George Dimopoulos

doi:10.3791/233

Cite this Article: Building a Better Mosquito: Identifying the Genes Enabling Malaria and Dengue Fever Resistance in A. gambiae and A. aegypti Mosquitoes

Dimopoulos, G. Building a Better Mosquito: Identifying the Genes Enabling Malaria and Dengue Fever Resistance in A. gambiae and A. aegypti Mosquitoes. J. Vis. Exp. (5), e233, doi:10.3791/233 (2007).

Abstract: Building a Better Mosquito: Identifying the Genes Enabling Malaria and Dengue Fever Resistance in A. gambiae and A. aegypti Mosquitoes

In this interview, George Dimopoulos focuses on the physiological mechanisms used by mosquitoes to combat Plasmodium falciparum and dengue virus infections. Explanation is given for how key refractory genes, those genes conferring resistance to vector pathogens, are identified in the mosquito and how this knowledge can be used to generate transgenic mosquitoes that are unable to carry the malaria parasite or dengue virus.

Disclosures: Building a Better Mosquito: Identifying the Genes Enabling Malaria and Dengue Fever Resistance in A. gambiae and A. aegypti Mosquitoes

The authors have nothing to disclose.

Ask the Author: Building a Better Mosquito: Identifying the Genes Enabling Malaria and Dengue Fever Resistance in A. gambiae and A. aegypti Mosquitoes

2 Comments

HOW CAN I DOWNLOAD

Posted by: AnonymousNovember 2, 2007, 10:47 AM

Is there any phylogenetic relationship between aedes and anopheles mosquito?

Posted by: ShalluMarch 16, 2009, 11:31 AM

Post a Question / Comment / Request

You must be signed in to post a comment. Please sign in or create an account.

Date Published	7/04/2007
JoVE Section	General
JoVE Issue	5
Comments	2 Comments
View Count	Loading... (Details…)
DOI	doi:10.3791/233