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De Gespaard Nerve Injury (SNI) Model van Induced mechanische allodynie in Muizen
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De Gespaard Nerve Injury (SNI) Model van Induced mechanische allodynie in Muizen

Article DOI: 10.3791/3092-v • 07:45 min • August 18th, 2011
August 18th, 2011 •
1, 2, 1, 1
1The Lundbeck Foundation Research Center MIND, Department of Biomedicine, Aarhus University, 2Department of Pharmacology and Pharmacotherapy, Faculty of Pharmaceutical Sciences, University of Copenhagen

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De Gespaard zenuwletsel diermodel is hier beschreven als een muis model van perifere neuropathische pijn na een gedeeltelijke denervatie van de nervus ischiadicus door lesioning het scheenbeen en de gemeenschappelijke peroneus takken, waardoor de resterende Sural zenuw intact. Gedragsverandering als gevolg van mechanische allodynie wordt gekwantificeerd door von Frey filamenten.

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Neurowetenschappen bil letsel PNS Mechanical allodynie Neuropathische pijn von Frey
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