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Experimentell generationens Cancer Associated-fibroblasts (CAFS) från Human bröst fibroblasts
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Experimentell generationens Cancer Associated-fibroblasts (CAFS) från Human bröst fibroblasts

Article DOI: 10.3791/3201-v • 15:43 min • October 25th, 2011
October 25th, 2011 •
*1, *1, 1,2
1CR-UK Stromal-Tumour Interaction Group, Paterson Institute for Cancer Research, University of Manchester, 2Atopy Research Center, Juntendo University
* These authors contributed equally

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Cancer-associerade fibroblaster (CAFS) med rik myofibroblaster vistas i tumören glatta spela en viktig roll i att driva tumörtillväxt. Vi utvecklade en coimplantation modell tumör xengraft för experimentellt generera CAFS från mänsklig bröst fibroblaster. Protokollet beskriver hur man kan upprätta CAF myofibroblaster att förvärva en förmåga att främja tumourigenesis.

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Medicin 56 cancer stromaceller myofibroblaster genereras experimentellt cancer-associerade fibroblaster (exp-CAFS) fibroblaster mänskliga bröst cancer tumörxenografter
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