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Geração Experimental de Carcinoma Associado fibroblastos (FAC) de Fibroblastos Humanos mamária
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Geração Experimental de Carcinoma Associado fibroblastos (FAC) de Fibroblastos Humanos mamária

Article DOI: 10.3791/3201-v • 15:43 min • October 25th, 2011
October 25th, 2011 •
*1, *1, 1,2
1CR-UK Stromal-Tumour Interaction Group, Paterson Institute for Cancer Research, University of Manchester, 2Atopy Research Center, Juntendo University
* These authors contributed equally

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Carcinoma associado fibroblastos (FAC) rico em miofibroblastos presentes no estroma tumoral, desempenhar um papel importante na condução de progressão do tumor. Nós desenvolvemos um modelo coimplantation xengraft tumor para gerar FAC experimentalmente a partir de fibroblastos humanos mamária. O protocolo descreve como estabelecer miofibroblastos CAF que adquirem uma capacidade de promover tumourigenesis.

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Medicina Edição 56 câncer miofibroblastos estromais experimentalmente gerados carcinoma-associada fibroblastos (exp-FAC) de fibroblastos humanos carcinomas de mama tumor xenoenxertos
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