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Impianto di un bracciale carotidea per innescare Shear-stress aterosclerosi indotta in topi
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Impianto di un bracciale carotidea per innescare Shear-stress aterosclerosi indotta in topi

Article DOI: 10.3791/3308-v • 07:52 min • January 13th, 2012
January 13th, 2012 •
1, 2,3, 1, 3, 2, 4, 4, 1, 1
1European Institute for Molecular Imaging, Westfälische Wilhelms-University Münster, 2British Heart Foundation Cardiovascular Sciences Unit, Imperial College London, 3Department of Bioengineering, Imperial College London, 4Biomedical Engineering, Eindhoven University of Technology

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Il bracciale costrizione presentate in questo articolo è stato progettato per indurre l'aterosclerosi nel topo arteria carotide comune. Grazie alla forma conica del suo lume interno del bracciale impiantato genera regioni ben definite della bassa, la tensione alta e oscillatorio taglio innescare lo sviluppo di lesioni aterosclerotiche dei diversi fenotipi infiammatori.

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Medicina Numero 59 l'aterosclerosi il mouse malattie cardiovascolari sforzo di taglio
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