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A Contusive Model of Unilateral Cervical Spinal Cord Injury Using the Infinite Horizon Impactor

Article DOI: 10.3791/3313-v • 07:28 min • July 24th, 2012
July 24th, 2012 •
1, 1, 1, 1, 1, 1, 1,2
1International Collaboration on Repair Discoveries (ICORD), University of British Columbia, 2Department of Orthopaedics, University of British Columbia

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Summary
Automatic Translation

A reliable and repeatable way to produce a cervical unilateral spinal cord injury using the Infinite Horizon impactor is described. The method takes advantage of a custom designed frame and clamp to stabilize the spine. The standardized procedure and biomechanical injury parameters result in sufficient and sustained injuries.

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Contusive Model Unilateral Cervical Spinal Cord Injury Infinite Horizon Impactor Animal Models Spinal Cord Injury Thoracic Spinal Cord Blunt Trauma Non-penetrating Trauma Clinically Relevant Injury Models Preclinical Evaluation Novel Treatments Contusion SCI Cervical Spinal Cord Technical Aspects Anatomical Outcomes Behavioral Outcomes Laminectomy Impact Force Impact Trajectory Impact Location Functional Recovery
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