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Kvantitative Sammenligning av Cis-Regulatory Element (CRE) Aktiviteter i Transgen Drosophila melanogaster
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Kvantitative Sammenligning av Cis-Regulatory Element (CRE) Aktiviteter i Transgen Drosophila melanogaster

Article DOI: 10.3791/3395-v • 08:19 min • December 19th, 2011
December 19th, 2011 •
1, 2
1Department of Biology, University of Dayton, 2Department of Biology, Center for Tissue Regeneration and Engineering at Dayton, University of Dayton

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Fenotypisk variasjon for trekk kan skyldes mutasjoner i cis-regulerende element (CRE) sekvenser som kontrollerer genuttrykk mønstre. Metoder utledet for bruk i Drosophila melanogaster kan kvantitativt sammenligne nivåene av romlige og tidsmessige mønstre av genuttrykk mediert av modifisert eller naturlig forekommende CRE varianter.

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Developmental Biology Cis-regulatoriske element CRE cis-regulatoriske modul Enhancer stedsspesifikke integrasjon reporter transgener konfokalmikroskopi regulatoriske logikk transkripsjonsfaktorer bindingssteder,
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