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Journal / Bioengineering / Lav Molekylær Vægt Protein berigelse mesoporøse…
JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
Lav Molekylær Vægt Protein berigelse mesoporøse silica Tynde Film til biomarkør Discovery
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Lav Molekylær Vægt Protein berigelse mesoporøse silica Tynde Film til biomarkør Discovery

Article DOI: 10.3791/3876-v • 13:00 min • April 17th, 2012
April 17th, 2012 •
1,2, 1, 1, 1, 1, 1, 1
1Department of Nanomedicine, The Methodist Hospital Research Institute, 2CAS Key Laboratory for Biological Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology

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Vi udviklet en teknik baseret på mesoporøse silica tynd film til selektiv genvinding af proteiner med lav molekylvægt og peptider fra humant serum. De fysisk-kemiske egenskaber af vores mesoporøse chips blev fintunet til at yde omfattende kontrol i peptid berigelse og dermed profilere serum proteom til diagnostiske formål.

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Bioengineering nanoporøse silica chip lav molekylvægt proteomics og Peptidomics og MALDI-TOF-massespektrometri tidlig diagnostik proteomics
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