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Journal / Medicine / 膵臓腺癌組織のパラフィン包埋したスライド上のB7-H1（PD-L1）の免疫組織化学的染色…
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膵臓腺癌組織のパラフィン包埋したスライド上のB7-H1（PD-L1）の免疫組織化学的染色
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膵臓腺癌組織のパラフィン包埋したスライド上のB7-H1（PD-L1）の免疫組織化学的染色

Article DOI: 10.3791/4059-v • 10:11 min • January 3rd, 2013
January 3rd, 2013 •
1,2, 1,2, 1,2,3, 1, 1,2,4, 3,5, 6, 1,2,5,7,8, 1,2,5,8, 1,2,4,5,7
1The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 2Department of Oncology, The Johns Hopkins University School of Medicine, 3Department of Dermatology, The Johns Hopkins University School of Medicine, 4Department of Surgery, Johns Hopkins University School of Medicine, 5The Sol Goldman Pancreatic Cancer Center, The Johns Hopkins University School of Medicine, 6Yale Cancer Center, Yale School of Medicine, 7The Skip Viragh Center for Pancreatic Cancer, The Johns Hopkins University School of Medicine, 8Department of Pathology, The Johns Hopkins University School of Medicine

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B7-H1（PD-L1）とPD-1への結合は、腫瘍の微小環境における主要な腫瘍誘発免疫抑制信号を提供します。膵臓腺癌におけるB7-H1の発現と局在を特徴付けるための免疫組織化学的染色法はここで説明されます。

Tags

がん生物学、問題71、医学、免疫学、生化学、分子生物学、細胞生物学、化学、腫瘍学、免疫組織化学、B7-H1（PD-L1）、膵臓腺癌、膵臓癌、膵臓癌、T細胞免疫、癌
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