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A Novel Surgical Ansatz intratracheale Verabreichung von Wirkstoffen in einem Fetal Mouse Model
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A Novel Surgical Ansatz intratracheale Verabreichung von Wirkstoffen in einem Fetal Mouse Model

Article DOI: 10.3791/4219-v • 10:12 min • October 31st, 2012
October 31st, 2012 •
*1, *2, 2, 1, 3, 2, 2, 4, 5, 1, 2
1Molecular Virology and Gene Therapy, KU Leuven, 2Department of Woman and Child, KU Leuven, 3Neurobiology and Gene Therapy, KU Leuven, 4Division of Nuclear Medicine, KU Leuven, 5Biomedical NMR Unit/ MoSAIC, KU Leuven
* These authors contributed equally

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Wir entwickelten eine neuartige chirurgische Ansatz für intratracheale Verabreichung von Wirkstoffen in die Maus Fötus. Die Transportroute ist effizienter bei der Ausrichtung der fetalen Mauslungen als der üblicherweise verwendete intra-Fruchtwasser Injektion. Dieses Verfahren hat sich nicht in einem Mausmodell wurden bisher beschrieben.

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Medizin Heft 68 Fetal intratracheale intra-Fruchtwasser Cross-Förderung Lunge Mikrochirurgie Gentherapie Mäuse rAAV
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