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Journal / Immunology and Infection / Granulocyt-beroende autoantikroppar-inducerad…
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Immunology and Infection
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Granulocyt-beroende autoantikroppar-inducerad hudblåsor
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Granulocyt-beroende autoantikroppar-inducerad hudblåsor

Article DOI: 10.3791/4250-v • 12:24 min • October 12th, 2012
October 12th, 2012 •
1, 2, 1,3
1Department of Dermatology, University of Freiburg, 2Kepler High School Freiburg, 3Centre for Biological Signalling Studies (BIOSS), University of Freiburg

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I djurmodellen som beskrivs i vårt nuvarande arbete, renade IgG-antikroppar mot en sträcka av 200 aminosyror (aa 757-967) av kollagen VII injiceras upprepade gånger i möss återger blåsbildning fenotypen samt histo-och immunopatologiska egenskaper karakteristiska för humant epidermolysis bullosa acquisita (EBA)

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Immunologi 68 medicin fysiologi anatomi dermatologi autoimmunitet kollagen VII inflammation extracellulär matris Fc-receptorn komplement granulocyt antikropp
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