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Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model

Article DOI: 10.3791/4422-v • 08:58 min • May 21st, 2013
May 21st, 2013 •
1,2, 3, 2, 1, 3, *2,4, *1
1Department of Orthopaedic Sports Medicine, Klinikum rechts der Isar der Technischen Universität München, 2Department of Radiology, Klinikum rechts der Isar der Technischen Universität München, 3Institute of Experimental Oncology and Therapy Research, Klinikum rechts der Isar der Technischen Universität München, 4Department of Radiology, Uniklinik Köln
* These authors contributed equally

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Summary
Automatic Translation

An experimental technique for the treatment of chondral defects in the rabbit's knee joint is described. The implantation of autologous chondrocytes seeded on a matrix is a well-accepted method for the remodeling and repair of articular cartilage lesions providing satisfying long-term results. Matrix-assisted autologous chondrocyte transplantation (MACT) offers a standardized and clinically established implantation method.

Tags

Matrix-assisted Autologous Chondrocyte Transplantation Chondral Defects Rabbit Model Articular Cartilage Self-regeneration Cartilage Lesions Surgical Techniques Hyaline Articular Cartilage Long-term Recovery Regenerative Techniques Tissue Engineering Fibrous Tissue Formation Fibrocartilaginous Tissue Formation Chondrogenic Potential Transplanted Cells Regenerative Cartilage Therapies Autologous Chondrocyte Implantation (ACI) Large Hyaline Cartilage Defects
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