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Evaluation of Muscle Function of the Extensor Digitorum Longus Muscle Ex vivo and Tibialis Anterior Muscle In situ in Mice
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Evaluation of Muscle Function of the Extensor Digitorum Longus Muscle Ex vivo and Tibialis Anterior Muscle In situ in Mice

Article DOI: 10.3791/50183-v • 14:36 min • February 9th, 2013
February 9th, 2013 •
1, 1, 1
1Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri

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Summary
Automatic Translation

Changes in limb muscle contractile and passive mechanical properties are important biomarkers for muscle diseases. This manuscript describes physiological assays to measure these properties in the murine extensor digitorum longus and tibialis anterior muscles.

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Muscle Function Extensor Digitorum Longus Muscle Tibialis Anterior Muscle Ex Vivo In Situ Mice Skeletal Muscle Myofibers Intramuscular Connective Tissues Myofibrils Sarcomeres Actin Filaments Myosin Filaments Z Discs Titin Protein Contractile Properties Force Generation Muscle Relaxation Factors Affecting Muscle Contraction Calcium Homeostasis ATP/ADP Ratio Passive Properties Stiffness Viscosity Extracellular Components Intracellular Components Connective Tissues
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