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Immunology and Infection

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JoVE Journal Immunology and Infection
PRP as a New Approach to Prevent Infection
A Multi-well Format Polyacrylamide-based Assay for Studying the Effect of Extracellular Matrix Stiffness on the Bacterial Infection of Adherent Cells
Journal (Immunology and Infection)
A Multi-well Format Polyacrylamide-based Assay for Studying the Effect of Extracellular Matrix Stiffness on the Bacterial Infection of Adherent Cells
A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
Journal (Immunology and Infection)
A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
 

PRP as a New Approach to Prevent Infection: Preparation and In vitro Antimicrobial Properties of PRP

Article DOI: 10.3791/50351-v • 06:36 min • April 9th, 2013
April 9th, 2013 •
1,2, 1,3,4
1Department of Orthopaedics, School of Medicine, West Virginia University, 2Department of Orthopaedics, Stem Cell Research Center, University of Pittsburgh, 3WVNano Initiative, 4Mary Babb Randolph Cancer Center

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Summary
Automatic Translation

Implant-associated infection is a significant clinical complication. This study describes an approach using platelet-rich plasma (PRP) to prevent implant-associated infections, presents the protocol for preparing PRP with constant platelet concentration, and reports the newly identified antimicrobial properties of PRP and related protocols for examining such antimicrobial properties in vitro.

Tags

PRP Platelet-rich Plasma Implant-associated Infection Antimicrobial Properties Antibiotic Resistance Healthcare Industry Clinical Applications Orthopaedic Surgeries Periodontal Surgeries Oral Surgeries Maxillofacial Surgeries Plastic Surgeries Sports Medicine Alternative To Antibiotics Infection Prevention Healing-promoting Properties Antibiotic Resistance Prevention
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