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Sex Stratified Neuronal Cultures to Study Ischemic Cell Death Pathways
 

Sex Stratified Neuronal Cultures to Study Ischemic Cell Death Pathways

Article DOI: 10.3791/50758-v 10:44 min December 9th, 2013
December 9th, 2013

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Summary

Primary disassociated embryonic hippocampal neuronal cultures are useful for investigating the signaling mechanisms involved in neuron death. Sexing the embryos before the isolation and dissociation of the hippocampus allows the preparation of separate male and female cultures, which enables the researcher to identify and investigate sex-specific cell signaling.

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Sex Stratified Neuronal Cultures Ischemic Cell Death Pathways Sex Differences In Neuronal Susceptibility Neurodegenerative Disease Signaling Mechanisms Primary Disassociated Embryonic Neuronal Culture Neuronal Cell Signaling Ischemia Disease Sex Steroid Treatment Female Brain Response To Hormones Male Brain Response To Hormones Neonate Rodents Response To Ischemic Injury Mixed Sex Neuronal Cultures Experimental Results Herson Lab University Of Colorado School Of Medicine
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