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Journal / Immunology and Infection / Hurtig screening af HIV revers transkriptase og…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Hurtig screening af HIV revers transkriptase og Integrase hæmmere
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Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
Journal (Immunology and Infection)
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Hurtig screening af HIV revers transkriptase og Integrase hæmmere

Article DOI: 10.3791/51400-v • 05:46 min • April 9th, 2014
April 9th, 2014 •
1, 1
1HIV Drug Resistance Program, National Cancer Institute

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Her beskriver vi cellulær cytotoksicitet og enkelt runde infektivitet analyser, som giver mulighed for hurtig og præcis screening af forbindelser for at bestemme deres cellulære cytotoksicitet (CC 50) og IC50-værdier mod WT og resistent HIV-1 lægemiddel.

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Immunologi HIV cytotoksicitet infektivitet luciferase resistens integrase reverse transkriptase
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