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Journal / Behavior / Behavioral Phenotyping of Murine Disease Models…
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Behavior

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JoVE Journal Behavior
Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)
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Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)

Article DOI: 10.3791/51524-v • 12:18 min • April 23rd, 2015
April 23rd, 2015 •
1, 2, 2, 2, 2, 3
1Department of Psychiatry and Behavioral Neurosciences, McMaster University, 2Department of Psychology, Neuroscience & Behaviour, McMaster University, 3Neuroscience Program, McMaster University

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Summary
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Prolonged and comprehensive monitoring of mice in a home-cage environment provides a deeper understanding of aberrant behavior in murine models of brain diseases. This paper describes the Integrated Behavioral Station (INBEST) as the key component of contemporary behavioral analysis.

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Behavioral Phenotyping Murine Disease Models Integrated Behavioral Station INBEST Genetic Engineering Small Rodents Biomedical Research Chronic CNS Disorders Behavioral Level Pathogenic Mechanisms Functional Deficits Peripheral Pathology Battery Of Tests Video-tracking Behavioral Spectroscopy Physiological Measures Home-base-like Setting Phenotyping Protocol Monitoring Apparatus Basic Functional Outputs Spontaneous Activity Food/water Intake Motivated Behavior Stress-free Environment Reproducibility Standardization
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