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A Murine Model of Arterial Restenosis
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A Murine Model of Arterial Restenosis: Technical Aspects of Femoral Wire Injury

Article DOI: 10.3791/52561-v • 06:42 min • March 10th, 2015
March 10th, 2015 •
1, 1, 1, 1, 1, 1, 1, 1, 1, 1
1Department of Surgery, University of Wisconsin School of Medicine and Public Health

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Summary
Automatic Translation

The mouse femoral artery wire injury model of restenosis is technically challenging. In this protocol we show the key technical details essential for successfully performing wire injury to induce consistent neointima for studies of restenosis.

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Murine Model Arterial Restenosis Technical Aspects Femoral Wire Injury Cardiovascular Disease Atherosclerosis Vessel Lumen Narrowing Atherosclerotic Plaque Development Rupturing Plaques Blood Flow Interruption Myocardial Infarction Stroke Endovascular Procedures Angioplasty Vessel Wall Damage Vascular Endothelium Damage Healing Response Neointimal Plaque Development Vessel Restenosis Animal Models Of Restenosis Pathophysiological Mechanisms Translational Approaches Femoral Artery Wire Injury Model Technical Difficulty
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