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Journal / Behavior / An Operant Intra-/Extra-dimensional Set-shift…
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Behavior

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JoVE Journal Behavior
An Operant Intra-/Extra-dimensional Set-shift Task for Mice
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An Operant Intra-/Extra-dimensional Set-shift Task for Mice

Article DOI: 10.3791/53503-v • 08:35 min • January 22nd, 2016
January 22nd, 2016 •
1, 1
1Department of Neuroscience and Brain Technologies, Istituto Italiano di Tecnologia

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Summary
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Attentional set-shifting cognitive abnormalities are a core feature of many psychiatric diseases. Here, we present the development of a novel automatic system for the effective study of attentional set-shifting abilities, executive functions and other cognitive abilities in mice with high translational validity to human studies.

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Operant Intra-dimensional Extra-dimensional Set-shift Task Mice Automated Task Executive Functions Cognitive Neuroscience Psychiatric Disorders Selective Cognitive Functions Pharmacological Treatment Automated Technique Objective Results Flexibility Diagnosis Treatment Executive Dysfunctions Large Drug Screenings Genetic Screenings Cognitive Symptoms Visual Demonstration Setup Experiment Protocol
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