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Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats
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Transarterial Administration of Oncolytic Viruses for Locoregional Therapy of Orthotopic HCC in Rats

Article DOI: 10.3791/53757-v • 08:55 min • April 15th, 2016
April 15th, 2016 •
1, 2, 3, 4, 5, 5, 1
1II. Medizinische Klinik, Klinikum rechts der Isar der TU München, 2Department of Nuclear Medicine, Klinikum rechts der Isar der TU München, 3Division of Clinical Oncology, Hiroshima Prefectural Hospital, 4Center for Preclinical Research, Klinikum rechts der Isar der TU München, 5Institute for Diagnostic and Interventional Radiology, Klinikum rechts der Isar der TU München

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Summary
Automatic Translation

Oncolytic virotherapies are under development as novel therapeutics for the treatment of hepatocellular carcinoma (HCC). Here we describe a method for locoregional therapy of HCC via hepatic arterial administration of oncolytic virus.

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Transarterial Administration Oncolytic Viruses Locoregional Therapy Orthotopic HCC Surgical Intervention Hepatic Arterial Administration Oncolytic Virus Therapy HCC Lesions Efficacy Of Locoregionally Applied Therapy High Titers Of Oncolytic Virus Intratumoral Administration Systemic Administration Transarterial Chemoembolization Standard Of Care Personal Protective Equipment Disinfect Surgical Area And Equipment Diluted Virus Concentration Toxicity Of The Virus Strain Of Rat Being Used Syringes With Needles Sedation Of Rat Small Incision In The Skin
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