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Journal / Immunology and Infection / Murine Full-thickness Skin Transplantation
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Immunology and Infection

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JoVE Journal Immunology and Infection
Murine Full-thickness Skin Transplantation
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Murine Full-thickness Skin Transplantation

Article DOI: 10.3791/55105-v • 07:59 min • January 2nd, 2017
January 2nd, 2017 •
*1,2, *1,2, *3, 3, 3, 1, 3
1Sidney-Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 2Department of Liver and Transplantation Surgery, Chang-Gung Transplantation Institute, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, 3Vascularized Composite Allotransplantation Laboratory, Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine
* These authors contributed equally

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Summary
Automatic Translation

Murine full-thickness skin transplantation is a well-established model to study rejection in an alloimmune setting. Here, we provide a tutorial of each step involved in performing a BALB/c-->C57BL/6 full-thickness skin transplant.

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Murine Skin Transplantation Full-thickness Alloimmune Responses Graft Rejection Immunological Reaction Secondary Skin Transplantation Donor-matched Third-party Skin Grafts Anesthetizing Electric Razor Disinfect Scissors Blunt Dissection Harvest Microscope Fine Tenotomy Scissors Connective Tissue Panniculus Carnosus Graft Bed PBS Petri Dish Recipient Mouse
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