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Cancer Research

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JoVE Journal Cancer Research
Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields)
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Determining the Optimal Inhibitory Frequency for Cancerous Cells Using Tumor Treating Fields (TTFields)

Article DOI: 10.3791/55820-v • 08:14 min • May 4th, 2017
May 4th, 2017 •
1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 2, 3, 2
1Preclinical Research Department, Novocure Ltd., Haifa, Israel, 2Novocure Ltd., Haifa, Israel, 3Novocure GmbH, Lucerne, Switzerland

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Summary
Automatic Translation

Tumor Treating Fields (TTFields) are an effective anti-tumor treatment modality delivered via the continuous, noninvasive application of low-intensity, intermediate-frequency, alternating electric fields. TTFields application to cell lines using a TTFields in vitro application system allows for the determination of the optimal frequency that leads to the highest reduction in cell counts.

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TTFields Inhibitory Frequency Cancerous Cells Tumor Treating Fields Optimal Frequency In Vitro Application System Clinical Administration Treatment Outcome TTField Parameters Pre-clinical Identification Specific Cancer Cell Line Combined Treatment Chemotherapy Agents Radiation Therapy Yaara Porat Researcher TTFields Dishes Base Plate Control Cells Coverslip U-87 MG Cells DMEM Medium Cell Overgrowth
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