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Porcine Model of Infrarenal Abdominal Aortic Aneurysm
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Porcine Model of Infrarenal Abdominal Aortic Aneurysm

Article DOI: 10.3791/60169-v • 11:13 min • November 21st, 2019
November 21st, 2019 •
1, 1, 1, 1, 1, 1, 1, 2, 3, *1, *1,4, *3
1Department of Surgery, University of Virginia School of Medicine, 2Department of Surgery, Ochsner Medical Center, 3Department of Surgery, University of Florida, 4The Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine
* These authors contributed equally

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Summary
Automatic Translation

This novel model creates robust infrarenal abdominal aortic aneurysms in swine using a combination of balloon angioplasty, elastase/collagenase perfusion, topical elastase application, and oral compound β-aminopropionitrile administration, which interferes with collagen cross-linking.

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Porcine Model Infrarenal Abdominal Aortic Aneurysm Large Animal Models Novel Technologies Treatments Elastase BAPN Chronic Aneurysmal Disease Thrombi Dissections Ruptures Surgical Residents Sedation Instruments Laparotomy Abdominal Cavity Electrocautery Retroperitoneum
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