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Interview: HIV-1 Provirus-DNA Excision Mit einem Evolved Rekombinase

Article DOI: 10.3791/793-v • 10:21 min • June 16th, 2008
June 16th, 2008 •
1
1Department of Cell Biology and Virology, Heinrich-Pette-Institute for Experimental Virology and Immunology, University of Hamburg

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Aktuelle HIV-1-Strategien handeln, um den viralen Lebenszyklus zu unterdrücken, aber nicht effektiv beseitigen Infektion. Hier zeigen wir, dass ein technisch Rekombinase effizient Verbrauchsteuern integrierte HIV-1 Provirus-DNA aus dem Genom der infizierten Zellen.

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Medizin Ausgabe 16 HIV Zellbiologie Rekombinase Provirus HeLa Zellen
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