David C. Spray Department of Neuroscience Albert Einstein College of Medicine Biography Publications Institution JoVE Articles David C. Spray has not added a biography. If you are David C. Spray and would like to personalize this page please email our Author Liaison for assistance. Publications Age-Related Changes in Neurons and Satellite Glial Cells in Mouse Dorsal Root Ganglia International Journal of Molecular Sciences. Jan, 2023 | Pubmed ID: 36769006 Activity and Stability of Panx1 Channels in Astrocytes and Neuroblastoma Cells Are Enhanced by Cholesterol Depletion Cells. Oct, 2022 | Pubmed ID: 36291086 Glioblastoma-Astrocyte Connexin 43 Gap Junctions Promote Tumor Invasion Molecular Cancer Research : MCR. Feb, 2022 | Pubmed ID: 34654721 Cx43 Carboxyl Terminal Domain Determines AQP4 and Cx30 Endfoot Organization and Blood Brain Barrier Permeability Scientific Reports. Dec, 2021 | Pubmed ID: 34934080 Pannexin-1 Channel Opening is Critical for COVID-19 Pathogenesis IScience. Dec, 2021 | Pubmed ID: 34841222 Estrogen Depletion on In Vivo Osteocyte Calcium Signaling Responses to Mechanical Loading Bone. Nov, 2021 | Pubmed ID: 34171514 The Roles of Calmodulin and CaMKII in Cx36 Plasticity International Journal of Molecular Sciences. Apr, 2021 | Pubmed ID: 33922931 Retinal Genomic Fabric Remodeling After Optic Nerve Injury Genes. 03, 2021 | Pubmed ID: 33799827 Generation and Characterization of Immortalized Mouse Cortical Astrocytes From Wildtype and Connexin43 Knockout Mice Frontiers in Cellular Neuroscience. 2021 | Pubmed ID: 33790744 Author Correction: Emerging Importance of Satellite Glia in Nervous System Function and Dysfunction Nature Reviews. Neuroscience. Dec, 2020 | Pubmed ID: 33093636 The Dynamic Nexus: Gap Junctions Control Protein Localization and Mobility in Distinct and Surprising Ways Scientific Reports. Oct, 2020 | Pubmed ID: 33046777 Emerging Importance of Satellite Glia in Nervous System Function and Dysfunction Nature Reviews. Neuroscience. Sep, 2020 | Pubmed ID: 32699292 Promotes Transcriptomic Remodeling of the JAK/STAT Signaling and Cell Cycle Pathways in Myoblasts Frontiers in Cellular and Infection Microbiology. 2020 | Pubmed ID: 32626662 Author Correction: Stress Gates an Astrocytic Energy Reservoir to Impair Synaptic Plasticity Nature Communications. Jun, 2020 | Pubmed ID: 32528004 Cellular Environment Remodels the Genomic Fabrics of Functional Pathways in Astrocytes Genes. May, 2020 | Pubmed ID: 32392822 Stress Gates an Astrocytic Energy Reservoir to Impair Synaptic Plasticity Nature Communications. Apr, 2020 | Pubmed ID: 32332733 Apoptotic Osteocytes Induce RANKL Production in Bystanders Via Purinergic Signaling and Activation of Pannexin Channels Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. May, 2020 | Pubmed ID: 31910292 Tubulin-Dependent Transport of Connexin-36 Potentiates the Size and Strength of Electrical Synapses Cells. Sep, 2019 | Pubmed ID: 31557934 Introduction to Connexins and Pannexins in the Healthy and Diseased Nervous System with Thanks to Felikas Bukauskas Neuroscience Letters. Mar, 2019 | Pubmed ID: 30926049 Gap Junction Mediated Signaling Between Satellite Glia and Neurons in Trigeminal Ganglia Glia. May, 2019 | Pubmed ID: 30715764 Correction To: Green Tea Polyphenol Treatment is Chondroprotective, Anti-inflammatory and Palliative in a Mouse Posttraumatic Osteoarthritis Model Arthritis Research & Therapy. Jan, 2019 | Pubmed ID: 30606217 Gap Junctions, Pannexins and Pain Neuroscience Letters. Mar, 2019 | Pubmed ID: 28647288 Concentrative Transport of Antifolates Mediated by the Proton-Coupled Folate Transporter (SLC46A1); Augmentation by a HEPES Buffer Molecular Pharmacology. Mar, 2018 | Pubmed ID: 29326243 Functional Genomic Fabrics Are Remodeled in a Mouse Model of Chagasic Cardiomyopathy and Restored Following Cell Therapy Microbes and Infection. Mar, 2018 | Pubmed ID: 29158000 Potential Role for a Specialized β Integrin-based Structure on Osteocyte Processes in Bone Mechanosensation Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. Feb, 2018 | Pubmed ID: 29087614 Osteocyte Calcium Signals Encode Strain Magnitude and Loading Frequency in Vivo Proceedings of the National Academy of Sciences of the United States of America. Oct, 2017 | Pubmed ID: 29078317 Cysteine Residues in the Cytoplasmic Carboxy Terminus of Connexins Dictate Gap Junction Plaque Stability Molecular Biology of the Cell. Oct, 2017 | Pubmed ID: 28835376 Structural and Functional Consequences of Connexin 36 (Cx36) Interaction with Calmodulin Frontiers in Molecular Neuroscience. 2016 | Pubmed ID: 27917108 Glial Pannexin1 Contributes to Tactile Hypersensitivity in a Mouse Model of Orofacial Pain Scientific Reports. Dec, 2016 | Pubmed ID: 27910899 Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals Cell Metabolism. 09, 2016 | Pubmed ID: 27626200 Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain Neuron. Sep, 2016 | Pubmed ID: 27568517 P2X7R-Panx1 Complex Impairs Bone Mechanosignaling Under High Glucose Levels Associated with Type-1 Diabetes PloS One. 2016 | Pubmed ID: 27159053 Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria PLoS Pathogens. Mar, 2016 | Pubmed ID: 27031954 Effect of Mesenchymal Stem Cells and Mouse Embryonic Fibroblasts on the Development of Preimplantation Mouse Embryos In Vitro Cellular & Developmental Biology. Animal. Apr, 2016 | Pubmed ID: 26744031 Strain-induced Mechanotransduction Through Primary Cilia, Extracellular ATP, Purinergic Calcium Signaling, and ERK1/2 Transactivates CITED2 and Downregulates MMP-1 and MMP-13 Gene Expression in Chondrocytes Osteoarthritis and Cartilage. May, 2016 | Pubmed ID: 26687824 Pannexin-1 and P2X7-Receptor Are Required for Apoptotic Osteocytes in Fatigued Bone to Trigger RANKL Production in Neighboring Bystander Osteocytes Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Apr, 2016 | Pubmed ID: 26553756 The Speed of Swelling Kinetics Modulates Cell Volume Regulation and Calcium Signaling in Astrocytes: A Different Point of View on the Role of Aquaporins Glia. Jan, 2016 | Pubmed ID: 26413835 The Einstein-Brazil Fogarty: A Decade of Synergy Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]. 2015 | Pubmed ID: 26691452 Developments in the Management of Chagas Cardiomyopathy Expert Review of Cardiovascular Therapy. Dec, 2015 | Pubmed ID: 26496376 Connexin Type and Fluorescent Protein Fusion Tag Determine Structural Stability of Gap Junction Plaques The Journal of Biological Chemistry. Sep, 2015 | Pubmed ID: 26265468 Green Tea Polyphenol Treatment is Chondroprotective, Anti-inflammatory and Palliative in a Mouse Post-traumatic Osteoarthritis Model Arthritis Research & Therapy. Dec, 2014 | Pubmed ID: 25516005 Gap Junctional Communication in Health and Disease Frontiers in Physiology. 2014 | Pubmed ID: 25484867 Molecular Imaging, Biodistribution and Efficacy of Mesenchymal Bone Marrow Cell Therapy in a Mouse Model of Chagas Disease Microbes and Infection. Nov, 2014 | Pubmed ID: 25218054 Pannexin 1 Channels Play Essential Roles in Urothelial Mechanotransduction and Intercellular Signaling PloS One. 2014 | Pubmed ID: 25170954 Adipocytes in Both Brown and White Adipose Tissue of Adult Mice Are Functionally Connected Via Gap Junctions: Implications for Chagas Disease Microbes and Infection. Nov, 2014 | Pubmed ID: 25150689 Inhibitors of the 5-lipoxygenase Pathway Activate Pannexin1 Channels in Macrophages Via the Thromboxane Receptor American Journal of Physiology. Cell Physiology. Sep, 2014 | Pubmed ID: 25080488 Structural Order in Pannexin 1 Cytoplasmic Domains Channels (Austin, Tex.). 2014 | Pubmed ID: 24751934 Connexins Modulate Autophagosome Biogenesis Nature Cell Biology. May, 2014 | Pubmed ID: 24705551 Shear-induced Endothelial NOS Activation and Remodeling Via Heparan Sulfate, Glypican-1, and Syndecan-1 Integrative Biology : Quantitative Biosciences from Nano to Macro. Mar, 2014 | Pubmed ID: 24480876 Human Liver Cell Trafficking Mutants: Characterization and Whole Exome Sequencing PloS One. 2014 | Pubmed ID: 24466322 Mechanosensory Responses of Osteocytes to Physiological Forces Occur Along Processes and Not Cell Body and Require αVβ3 Integrin Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013 | Pubmed ID: 24324138 High Glucose Attenuates Shear-induced Changes in Endothelial Hydraulic Conductivity by Degrading the Glycocalyx PloS One. 2013 | Pubmed ID: 24260138 Disruption of Calcium Homeostasis in Cardiomyocytes Underlies Cardiac Structural and Functional Changes in Severe Sepsis PloS One. 2013 | Pubmed ID: 23935889 Matrix-dependent Adhesion Mediates Network Responses to Physiological Stimulation of the Osteocyte Cell Process Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23818616 Promises and Pitfalls of a Pannexin1 Transgenic Mouse Line Frontiers in Pharmacology. 2013 | Pubmed ID: 23675350 Gap Junctions and Bystander Effects: Good Samaritans and Executioners Wiley Interdisciplinary Reviews. Membrane Transport and Signaling. Jan, 2013 | Pubmed ID: 23565352 Identification of a Functional Prostanoid-like Receptor in the Protozoan Parasite, Trypanosoma Cruzi Parasitology Research. Apr, 2013 | Pubmed ID: 23403991 Mesenchymal Bone Marrow Cell Therapy in a Mouse Model of Chagas Disease. Where Do the Cells Go? PLoS Neglected Tropical Diseases. 2012 | Pubmed ID: 23272265 Connexin43 and Pannexin1 Channels in Osteoblasts: Who is the "hemichannel"? The Journal of Membrane Biology. Jul, 2012 | Pubmed ID: 22797941 Calmodulin Dependent Protein Kinase Increases Conductance at Gap Junctions Formed by the Neuronal Gap Junction Protein Connexin36 Brain Research. Dec, 2012 | Pubmed ID: 22796294 ATP Signaling is Deficient in Cultured Pannexin1-null Mouse Astrocytes Glia. Jul, 2012 | Pubmed ID: 22499153 Autophagy Modulates Dynamics of Connexins at the Plasma Membrane in a Ubiquitin-dependent Manner Molecular Biology of the Cell. Jun, 2012 | Pubmed ID: 22496425 Extracellular K⁺ and Astrocyte Signaling Via Connexin and Pannexin Channels Neurochemical Research. Nov, 2012 | Pubmed ID: 22481627 Pannexin1-mediated ATP Release Provides Signal Transmission Between Neuro2A Cells Neurochemical Research. Jun, 2012 | Pubmed ID: 22359052 Chagas Heart Disease: Report on Recent Developments Cardiology in Review. Mar-Apr, 2012 | Pubmed ID: 22293860 Glial Cells in (patho)physiology Journal of Neurochemistry. Apr, 2012 | Pubmed ID: 22251135 Functional and Transcriptomic Recovery of Infarcted Mouse Myocardium Treated with Bone Marrow Mononuclear Cells Stem Cell Reviews and Reports. Mar, 2012 | Pubmed ID: 21671060 Two Non-vesicular ATP Release Pathways in the Mouse Erythrocyte Membrane FEBS Letters. Nov, 2011 | Pubmed ID: 21983290 Gap Junctions and Chagas Disease Advances in Parasitology. 2011 | Pubmed ID: 21884887 Optimized Labeling of Bone Marrow Mesenchymal Cells with Superparamagnetic Iron Oxide Nanoparticles and in Vivo Visualization by Magnetic Resonance Imaging Journal of Nanobiotechnology. 2011 | Pubmed ID: 21542946 In Vitro Motility of Liver Connexin Vesicles Along Microtubules Utilizes Kinesin Motors The Journal of Biological Chemistry. Jul, 2011 | Pubmed ID: 21536677 Pannexin Channels Are Not Gap Junction Hemichannels Channels (Austin, Tex.). May-Jun, 2011 | Pubmed ID: 21532340 On the Electrophysiological Response of Bone Cells Using a Stokesian Fluid Stimulus Probe for Delivery of Quantifiable Localized PicoNewton Level Forces Journal of Biomechanics. Jun, 2011 | Pubmed ID: 21511259 Imaging the Endothelial Glycocalyx in Vitro by Rapid Freezing/freeze Substitution Transmission Electron Microscopy Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2011 | Pubmed ID: 21474821 Reversion of Gene Expression Alterations in Hearts of Mice with Chronic Chagasic Cardiomyopathy After Transplantation of Bone Marrow Cells Cell Cycle (Georgetown, Tex.). May, 2011 | Pubmed ID: 21467843 Silencing MaxiK Activity in Corporal Smooth Muscle Cells Initiates Compensatory Mechanisms to Maintain Calcium Homeostasis The Journal of Sexual Medicine. Aug, 2011 | Pubmed ID: 21269393 Alterations in the Brain Transcriptome in ANKA Infected Mice Journal of Neuroparasitology. Oct, 2010 | Pubmed ID: 23467761 Focal Inflammation Causes Carbenoxolone-Sensitive Tactile Hypersensitivity in Mice The Open Pain Journal. Jan, 2010 | Pubmed ID: 21151805 Persistent Cognitive and Motor Deficits After Successful Antimalarial Treatment in Murine Cerebral Malaria Microbes and Infection. Dec, 2010 | Pubmed ID: 20800692 Characterization of HTERT-immortalized Osteoblast Cell Lines Generated from Wild-type and Connexin43-null Mouse Calvaria American Journal of Physiology. Cell Physiology. Nov, 2010 | Pubmed ID: 20686067 Fluid Flow-induced Soluble Vascular Endothelial Growth Factor Isoforms Regulate Actin Adaptation in Osteoblasts The Journal of Biological Chemistry. Oct, 2010 | Pubmed ID: 20682775 Transcriptomic Signatures of Alterations in a Myoblast Cell Line Infected with Four Distinct Strains of Trypanosoma Cruzi The American Journal of Tropical Medicine and Hygiene. May, 2010 | Pubmed ID: 20439965 Trypanosoma Cruzi Infection Results in the Reduced Expression of Caveolin-3 in the Heart Cell Cycle (Georgetown, Tex.). Apr, 2010 | Pubmed ID: 20372051 Acquired Infection with Toxoplasma Gondii in Adult Mice Results in Sensorimotor Deficits but Normal Cognitive Behavior Despite Widespread Brain Pathology Microbes and Infection / Institut Pasteur. Jul, 2010 | Pubmed ID: 20348009 The Carboxyl-terminal Domain of Connexin43 is a Negative Modulator of Neuronal Differentiation The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20164188 Chemical Induction of Cardiac Differentiation in P19 Embryonal Carcinoma Stem Cells Stem Cells and Development. Mar, 2010 | Pubmed ID: 20163207 Modulatory Effects of CAMP and PKC Activation on Gap Junctional Intercellular Communication Among Thymic Epithelial Cells BMC Cell Biology. Jan, 2010 | Pubmed ID: 20078861 Bidirectional Calcium Signaling Between Satellite Glial Cells and Neurons in Cultured Mouse Trigeminal Ganglia Neuron Glia Biology. Feb, 2010 | Pubmed ID: 19891813 Mefloquine Blockade of Pannexin1 Currents: Resolution of a Conflict Cell Communication & Adhesion. Dec, 2009 | Pubmed ID: 20218915 Astrocytic 'power-grid': Delivery Upon Neuronal Demand Cellscience. Jan, 2009 | Pubmed ID: 19756252 Transcriptomic Alterations in Trypanosoma Cruzi-infected Cardiac Myocytes Microbes and Infection. Dec, 2009 | Pubmed ID: 19729072 Automated Cell-based Assay for Screening of Aquaporin Inhibitors Analytical Chemistry. Oct, 2009 | Pubmed ID: 19705854 Point Mutation in the Mouse P2X7 Receptor Affects Intercellular Calcium Waves in Astrocytes ASN Neuro. Apr, 2009 | Pubmed ID: 19570022 Cell Therapy in Chagas Disease Interdisciplinary Perspectives on Infectious Diseases. 2009 | Pubmed ID: 19547703 Pannexin 1: the Molecular Substrate of Astrocyte "hemichannels" The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2009 | Pubmed ID: 19474335 Perspectives on Trypanosoma Cruzi-induced Heart Disease (Chagas Disease) Progress in Cardiovascular Diseases. 2009 | Pubmed ID: 19410685 Trifluoroethanol Reveals Helical Propensity at Analogous Positions in Cytoplasmic Domains of Three Connexins Biopolymers. 2009 | Pubmed ID: 19226516 Effects of Ageing and Streptozotocin-induced Diabetes on Connexin43 and P2 Purinoceptor Expression in the Rat Corpora Cavernosa and Urinary Bladder BJU International. Jun, 2009 | Pubmed ID: 19154470 Reciprocal Influence of Connexins and Apical Junction Proteins on Their Expressions and Functions Biochimica Et Biophysica Acta. Apr, 2009 | Pubmed ID: 19046940 Connexins, Pannexins, Innexins: Novel Roles of "hemi-channels" Pflugers Archiv : European Journal of Physiology. Apr, 2009 | Pubmed ID: 18853183 The Neuronal Connexin36 Interacts with and is Phosphorylated by CaMKII in a Way Similar to CaMKII Interaction with Glutamate Receptors Proceedings of the National Academy of Sciences of the United States of America. Dec, 2008 | Pubmed ID: 19095792 IGF-I Regulates Tight-junction Protein Claudin-1 During Differentiation of Osteoblast-like MC3T3-E1 Cells Via a MAP-kinase Pathway Cell and Tissue Research. Nov, 2008 | Pubmed ID: 18855015 Effect of Microgravity on Gene Expression in Mouse Brain Experimental Brain Research. Nov, 2008 | Pubmed ID: 18704384 Similar Transcriptomic Alterations in Cx43 Knockdown and Knockout Astrocytes Cell Communication & Adhesion. May, 2008 | Pubmed ID: 18649190 Lack of "hemichannel" Activity in Insulin-producing Cells Cell Communication & Adhesion. May, 2008 | Pubmed ID: 18649186 Cognitive Dysfunction in Mice Infected with Plasmodium Berghei Strain ANKA The Journal of Infectious Diseases. Jun, 2008 | Pubmed ID: 18419550 Alterations in Myocardial Gene Expression Associated with Experimental Trypanosoma Cruzi Infection Genomics. May, 2008 | Pubmed ID: 18343633 Bone Marrow Cell Therapy Ameliorates and Reverses Chagasic Cardiomyopathy in a Mouse Model The Journal of Infectious Diseases. Feb, 2008 | Pubmed ID: 18237267 Trypanosoma Cruzi Induces Changes in Cardiac Connexin43 Expression Microbes and Infection. Jan, 2008 | Pubmed ID: 18068391 Aquaporin-4 Water Channels in Enteric Neurons Journal of Neuroscience Research. Feb, 2008 | Pubmed ID: 17893913 Alteration of Transcriptomic Networks in Adoptive-transfer Experimental Autoimmune Encephalomyelitis Frontiers in Integrative Neuroscience. 2007 | Pubmed ID: 18958238 Connexin and Pannexin Mediated Cell-cell Communication Neuron Glia Biology. Aug, 2007 | Pubmed ID: 18634611 Gap Junction Remodeling and Cardiac Arrhythmogenesis in a Murine Model of Oculodentodigital Dysplasia Proceedings of the National Academy of Sciences of the United States of America. Dec, 2007 | Pubmed ID: 18077386 Gap Junction and Purinergic P2 Receptor Proteins As a Functional Unit: Insights from Transcriptomics The Journal of Membrane Biology. Jun, 2007 | Pubmed ID: 17665085 Organizational Principles of the Connexin-related Brain Transcriptome The Journal of Membrane Biology. Aug, 2007 | Pubmed ID: 17657523 Fluid Shear Stress Upregulates Vascular Endothelial Growth Factor Gene Expression in Osteoblasts Annals of the New York Academy of Sciences. Nov, 2007 | Pubmed ID: 17646268 Connexin-dependent Transcellular Transcriptomic Networks in Mouse Brain Progress in Biophysics and Molecular Biology. 2007 | Pubmed ID: 17507080 The Gap Junction Protein Connexin32 Interacts with the Src Homology 3/hook Domain of Discs Large Homolog 1 The Journal of Biological Chemistry. Mar, 2007 | Pubmed ID: 17284442 Pannexin1 is Part of the Pore Forming Unit of the P2X(7) Receptor Death Complex FEBS Letters. Feb, 2007 | Pubmed ID: 17240370 Connexin43 and the Brain Transcriptome of Newborn Mice Genomics. Jan, 2007 | Pubmed ID: 17064878 Transfection of Mammalian Cells with Connexins and Measurement of Voltage Sensitivity of Their Gap Junctions Nature Protocols. 2006 | Pubmed ID: 17487162 Functional Connexin "hemichannels": a Critical Appraisal Glia. Nov, 2006 | Pubmed ID: 17006904 Transcriptomic Changes in Developing Kidney Exposed to Chronic Hypoxia Biochemical and Biophysical Research Communications. Oct, 2006 | Pubmed ID: 16934745 Cardiac Connexins: Genes to Nexus Advances in Cardiology. 2006 | Pubmed ID: 16646581 Microarray Technology in the Investigation of Diseases of Myocardium with Special Reference to Infection Frontiers in Bioscience : a Journal and Virtual Library. May, 2006 | Pubmed ID: 16368557 A Stochastic Two-dimensional Model of Intercellular Ca2+ Wave Spread in Glia Biophysical Journal. Jan, 2006 | Pubmed ID: 16214872 A Developmental Switch in the Expression of Aquaporin-4 and Kir4.1 from Horizontal to Müller Cells in Mouse Retina Investigative Ophthalmology & Visual Science. Oct, 2005 | Pubmed ID: 16186376 Sensitivity of the Brain Transcriptome to Connexin Ablation Biochimica Et Biophysica Acta. Jun, 2005 | Pubmed ID: 15955303 Connexin43, the Major Gap Junction Protein of Astrocytes, is Down-regulated in Inflamed White Matter in an Animal Model of Multiple Sclerosis Journal of Neuroscience Research. Jun, 2005 | Pubmed ID: 15898103 Regulation of Connexin43-protein Binding in Astrocytes in Response to Chemical Ischemia/hypoxia The Journal of Biological Chemistry. Mar, 2005 | Pubmed ID: 15618229 Genes Controlling Multiple Functional Pathways Are Transcriptionally Regulated in Connexin43 Null Mouse Heart Physiological Genomics. Feb, 2005 | Pubmed ID: 15585606 The Role of the Glycocalyx in Reorganization of the Actin Cytoskeleton Under Fluid Shear Stress: a "bumper-car" Model Proceedings of the National Academy of Sciences of the United States of America. Nov, 2004 | Pubmed ID: 15545600 Potent Block of Cx36 and Cx50 Gap Junction Channels by Mefloquine Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004 | Pubmed ID: 15297615 PH-dependent Dimerization of the Carboxyl Terminal Domain of Cx43 Biophysical Journal. Jul, 2004 | Pubmed ID: 15240490 Gene Expression Alterations in Connexin Null Mice Extend Beyond the Gap Junction Neurochemistry International. 2004 | Pubmed ID: 15145539 Alterations of Intercellular Communication in Neonatal Cardiac Myocytes from Connexin43 Null Mice Cardiovascular Research. May, 2004 | Pubmed ID: 15094359 Regulation of Connexin43 Protein Complexes by Intracellular Acidification Circulation Research. Feb, 2004 | Pubmed ID: 14699011 Following Tracks of Hemichannels Cell Communication & Adhesion. 2003 | Pubmed ID: 14681038 Kinetics of Protein-protein Interactions of Connexins: Use of Enzyme Linked Sorbent Assays Cell Communication & Adhesion. 2003 | Pubmed ID: 14681017 Array Analysis of Gene Expression in Connexin-43 Null Astrocytes Physiological Genomics. Nov, 2003 | Pubmed ID: 12928503 Microarray Analysis of Changes in Gene Expression in a Murine Model of Chronic Chagasic Cardiomyopathy Parasitology Research. Oct, 2003 | Pubmed ID: 12910413 Gap Junctions Mediate Bystander Cell Death in Developing Retina The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2003 | Pubmed ID: 12878681 Closure of Gap Junction Channels by Arylaminobenzoates Molecular Pharmacology. Jun, 2003 | Pubmed ID: 12761350 Acute Downregulation of Cx43 Alters P2Y Receptor Expression Levels in Mouse Spinal Cord Astrocytes Glia. Apr, 2003 | Pubmed ID: 12655600 Hits and Misses from Gene Expression Ratio Measurements in CDNA Microarray Studies Journal of Biomolecular Techniques : JBT. Sep, 2002 | Pubmed ID: 19498978 Improved Procedures to Mine Data Obtained from Spotted CDNA Arrays Journal of Biomolecular Techniques : JBT. Mar, 2002 | Pubmed ID: 19498959 Prospects for Rational Development of Pharmacological Gap Junction Channel Blockers Current Drug Targets. Dec, 2002 | Pubmed ID: 12448697 Formation of the Gap Junction Nexus: Binding Partners for Connexins Journal of Physiology, Paris. 2002 | Pubmed ID: 12445902 PH-dependent Intramolecular Binding and Structure Involving Cx43 Cytoplasmic Domains The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12151412 Connexin Family Members Target to Lipid Raft Domains and Interact with Caveolin-1 Biochemistry. May, 2002 | Pubmed ID: 11980479 Quinine Blocks Specific Gap Junction Channel Subtypes Proceedings of the National Academy of Sciences of the United States of America. Sep, 2001 | Pubmed ID: 11535816 Calmodulin Kinase Pathway Mediates the K+-induced Increase in Gap Junctional Communication Between Mouse Spinal Cord Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2001 | Pubmed ID: 11517253 Cytokine Regulation of Gap Junction Connectivity: an Open-and-shut Case or Changing Partners at the Nexus? The American Journal of Pathology. May, 2001 | Pubmed ID: 11337352 Evidence for Secretory Pathway Localization of a Voltage-dependent Anion Channel Isoform Proceedings of the National Academy of Sciences of the United States of America. Mar, 2000 | Pubmed ID: 10716730 Intercellular Communication in Spinal Cord Astrocytes: Fine Tuning Between Gap Junctions and P2 Nucleotide Receptors in Calcium Wave Propagation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2000 | Pubmed ID: 10662834 Wnt-1 Regulation of Connexin43 in Cardiac Myocytes The Journal of Clinical Investigation. Jan, 2000 | Pubmed ID: 10642594 Characteristics of Gap Junction Channels in Schwann Cells from Wild-Type and Connexin-Null Mice Annals of the New York Academy of Sciences. Oct, 1999 | Pubmed ID: 29086983 Functional Properties of Channels Formed by the Neuronal Gap Junction Protein Connexin36 The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 1999 | Pubmed ID: 10559394 IL-1beta Differentially Regulates Calcium Wave Propagation Between Primary Human Fetal Astrocytes Via Pathways Involving P2 Receptors and Gap Junction Channels Proceedings of the National Academy of Sciences of the United States of America. Sep, 1999 | Pubmed ID: 10500225 Voltage Dependence of Macroscopic and Unitary Currents of Gap Junction Channels Formed by Mouse Connexin50 Expressed in Rat Neuroblastoma Cells The Journal of Physiology. Jun, 1999 | Pubmed ID: 10358109 Increased Intercellular Communication in Mouse Astrocytes Exposed to Hyposmotic Shocks Glia. Sep, 1998 | Pubmed ID: 9700491 Calcium Waves Between Astrocytes from Cx43 Knockout Mice Glia. Sep, 1998 | Pubmed ID: 9700490 Changes in the Properties of Gap Junctions During Neuronal Differentiation of Hippocampal Progenitor Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 1998 | Pubmed ID: 9465000 C-erbB2/neu Transfection Induces Gap Junctional Communication Incompetence in Glial Cells The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 1996 | Pubmed ID: 8699242 A Fluorescent Intravital Imaging Approach to Study Load-Induced Calcium Signaling Dynamics in Mouse Osteocytes Karl J. Lewis1, James F. Boorman-Padgett3, Macy Castaneda2, David C. Spray4, Mia M. Thi5,6, Mitchell B. Schaffler3 1Meinig School of Biomedical Engineering, Cornell University, 2Sibley School of Mechanical and Aerospace Engineering, Cornell University, 3Department of Biomedical Engineering, The City College of New York, 4Department of Neuroscience, Albert Einstein College of Medicine, 5Department of Orthopaedic Surgery, Albert Einstein College of Medicine, 6Department of Molecular Pharmacology, Albert Einstein College of Medicine JoVE 64366 Bioengineering
A Fluorescent Intravital Imaging Approach to Study Load-Induced Calcium Signaling Dynamics in Mouse Osteocytes Karl J. Lewis1, James F. Boorman-Padgett3, Macy Castaneda2, David C. Spray4, Mia M. Thi5,6, Mitchell B. Schaffler3 1Meinig School of Biomedical Engineering, Cornell University, 2Sibley School of Mechanical and Aerospace Engineering, Cornell University, 3Department of Biomedical Engineering, The City College of New York, 4Department of Neuroscience, Albert Einstein College of Medicine, 5Department of Orthopaedic Surgery, Albert Einstein College of Medicine, 6Department of Molecular Pharmacology, Albert Einstein College of Medicine JoVE 64366 Bioengineering