Jesús Jiménez-Barbero

Publications

• Strategy for the Enzymatic Acylation of the Apple Flavonoid Phloretin Based on Prior α-Glucosylation
  Journal of Agricultural and Food Chemistry. Feb, 2024  |   Pubmed ID: 38350922
• Unraveling Molecular Recognition of Glycan Ligands by Siglec-9 Via NMR Spectroscopy and Molecular Dynamics Modeling
  ACS Chemical Biology. Feb, 2024  |   Pubmed ID: 38321945
• Correction to "Targeting the Spike: Repurposing Mithramycin and Dihydroergotamine to Block SARS-CoV-2 Infection"
  ACS Omega. Jan, 2024  |   Pubmed ID: 38313499
• The Impact of Glycosylation on the Structure, Function, and Interactions of CD14
  Glycobiology. Apr, 2024  |   Pubmed ID: 38227775
• Targeting the Spike: Repurposing Mithramycin and Dihydroergotamine to Block SARS-CoV-2 Infection
  ACS Omega. Nov, 2023  |   Pubmed ID: 38027314
• Identification of a New DC-SIGN Binding Pentamannoside Epitope Within the Complex Structure of Mannan
  Cell Surface (Amsterdam, Netherlands). Dec, 2023  |   Pubmed ID: 37520856
• Structural Insights into Siglec-15 Reveal Glycosylation Dependency for Its Interaction with T Cells Through Integrin CD11b
  Nature Communications. Jun, 2023  |   Pubmed ID: 37311743
• Total Synthesis and Structural Studies of Zwitterionic Polysaccharide A1 Fragments
  Journal of the American Chemical Society. Jun, 2023  |   Pubmed ID: 37310804
• Molecular Recognition of Glycan-Bearing Glycomacromolecules Presented at Membrane Surfaces by Lectins: An NMR View
  ACS Omega. May, 2023  |   Pubmed ID: 37214724
• Highly Diastereoselective Multicomponent Synthesis of Spirocyclopropyl Oxindoles Enabled by Rare-Earth Metal Salts
  Organic Letters. May, 2023  |   Pubmed ID: 37125666
• Development of Synthetic, Self-adjuvanting, and Self-assembling Anticancer Vaccines Based on a Minimal Saponin Adjuvant and the Tumor-associated MUC1 Antigen
  Chemical Science. Mar, 2023  |   Pubmed ID: 37006677
• New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity As Vaccine Adjuvants
  Journal of Medicinal Chemistry. Feb, 2023  |   Pubmed ID: 36728697
• Immobilization of Biantennary N-Glycans Leads to Branch Specific Epitope Recognition by LSECtin
  ACS Central Science. Oct, 2022  |   Pubmed ID: 36313162
• The Spike of SARS-CoV-2 Promotes Metabolic Rewiring in Hepatocytes
  Communications Biology. Aug, 2022  |   Pubmed ID: 35978143
• Assessing the Mobility of Severe Acute Respiratory Syndrome Coronavirus-2 Spike Protein Glycans by Structural and Computational Methods
  Frontiers in Microbiology. 2022  |   Pubmed ID: 35495643
• Atomic and Specificity Details of Mucin 1 -Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
  JACS Au. Mar, 2022  |   Pubmed ID: 35373202
• Unveiling the Role of Pyrylium Frameworks on π-stacking Interactions: a Combined and Experimental Study
  Physical Chemistry Chemical Physics : PCCP. Jan, 2022  |   Pubmed ID: 34633001
• Sulfation Code and Conformational Plasticity of L-Iduronic Acid Homo-Oligosaccharides Mimic the Biological Functions of Heparan Sulfate
  ACS Chemical Biology. Nov, 2021  |   Pubmed ID: 34586794
• Targeting Transthyretin in Alzheimer's Disease: Drug Discovery of Small-molecule Chaperones As Disease-modifying Drug Candidates for Alzheimer's Disease
  European Journal of Medicinal Chemistry. Dec, 2021  |   Pubmed ID: 34555615
• Epitope Recognition of a Monoclonal Antibody Raised Against a Synthetic Glycerol Phosphate Based Teichoic Acid
  ACS Chemical Biology. Aug, 2021  |   Pubmed ID: 34255482
• Cross-Linking Effects Dictate the Preference of Galectins to Bind LacNAc-Decorated HPMA Copolymers
  International Journal of Molecular Sciences. Jun, 2021  |   Pubmed ID: 34206141
• The Two Domains of Human Galectin-8 Bind Sialyl- and Fucose-containing Oligosaccharides in an Independent Manner. A 3D View by Using NMR
  RSC Chemical Biology. Apr, 2021  |   Pubmed ID: 34179785
• Selective C-Labels on Repeating Glycan Oligomers to Reveal Protein Binding Epitopes Through NMR: Polylactosamine Binding to Galectins
  Angewandte Chemie (International Ed. in English). Aug, 2021  |   Pubmed ID: 34128568
• Hypoxia Reduces Cell Attachment of SARS-CoV-2 Spike Protein by Modulating the Expression of ACE2, Neuropilin-1, Syndecan-1 and Cellular Heparan Sulfate
  Emerging Microbes & Infections. Dec, 2021  |   Pubmed ID: 34013835
• Galectin-4 N-Terminal Domain: Binding Preferences Toward A and B Antigens With Different Peripheral Core Presentations
  Frontiers in Chemistry. 2021  |   Pubmed ID: 33968903
• Glycosyl Oxocarbenium Ions: Structure, Conformation, Reactivity, and Interactions
  Accounts of Chemical Research. Jun, 2021  |   Pubmed ID: 33930267
• Exploration of Galectin Ligands Displayed on Gram-Negative Respiratory Bacterial Pathogens with Different Cell Surface Architectures
  Biomolecules. Apr, 2021  |   Pubmed ID: 33919637
• Minimal Epitope for Mannitou IgM on Paucimannose-carrying Glycoproteins
  Glycobiology. Sep, 2021  |   Pubmed ID: 33909073
• Synthesis and Chelation Study of a Fluoroionophore and a Glycopeptide Based on an Aza Crown Iminosugar Structure
  Carbohydrate Research. Mar, 2021  |   Pubmed ID: 33618101
• NMR of Glycoproteins: Profiling, Structure, Conformation and Interactions
  Current Opinion in Structural Biology. Jun, 2021  |   Pubmed ID: 33129067
• Bacterial Polysaccharides: Conformation, Dynamics and Molecular Recognition by Antibodies
  Drug Discovery Today. Technologies. Dec, 2020  |   Pubmed ID: 33388123
• Current Status on Therapeutic Molecules Targeting Siglec Receptors
  Cells. Dec, 2020  |   Pubmed ID: 33333862
• Fluorinated Carbohydrates As Lectin Ligands: Simultaneous Screening of a Monosaccharide Library and Chemical Mapping by F NMR Spectroscopy
  The Journal of Organic Chemistry. Dec, 2020  |   Pubmed ID: 33258593
• Structural Characterization of N-Linked Glycans in the Receptor Binding Domain of the SARS-CoV-2 Spike Protein and Their Interactions with Human Lectins
  Angewandte Chemie (International Ed. in English). Dec, 2020  |   Pubmed ID: 32915505
• Synthesis of Long-chain Alkyl Glucosides Via Reverse Hydrolysis Reactions Catalyzed by an Engineered β-glucosidase
  Enzyme and Microbial Technology. Oct, 2020  |   Pubmed ID: 32912700
• Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in Vivo Molecular Imaging Study1
  Journal of Alzheimer's Disease : JAD. 2020  |   Pubmed ID: 32804152
• Unravelling the Time Scale of Conformational Plasticity and Allostery in Glycan Recognition by Human Galectin-1
  Chemistry (Weinheim an Der Bergstrasse, Germany). Dec, 2020  |   Pubmed ID: 32780906
• An Assay for Screening Potential Drug Candidates for Alzheimer's Disease That Act As Chaperones of the Transthyretin and Amyloid-β Peptides Interaction
  Chemistry (Weinheim an Der Bergstrasse, Germany). Dec, 2020  |   Pubmed ID: 32761825
• The Interaction of Fluorinated Glycomimetics with DC-SIGN: Multiple Binding Modes Disentangled by the Combination of NMR Methods and MD Simulations
  Pharmaceuticals (Basel, Switzerland). Aug, 2020  |   Pubmed ID: 32759765
• Structural Basis of Noscapine Activation for Tubulin Binding
  Journal of Medicinal Chemistry. Aug, 2020  |   Pubmed ID: 32657585
• Scientific Response to the Coronavirus Crisis in Spain: Collaboration and Multidisciplinarity
  ACS Chemical Biology. Jul, 2020  |   Pubmed ID: 32584537
• Fluorinated Carbohydrates As Chemical Probes for Molecular Recognition Studies. Current Status and Perspectives
  Chemical Society Reviews. Jun, 2020  |   Pubmed ID: 32520059
• An Epoxide Intermediate in Glycosidase Catalysis
  ACS Central Science. May, 2020  |   Pubmed ID: 32490192
• Molecular Recognition in C-Type Lectins: The Cases of DC-SIGN, Langerin, MGL, and L-Sectin
  Chembiochem : a European Journal of Chemical Biology. Nov, 2020  |   Pubmed ID: 32426893
• Structure-Guided Design of a Group B Streptococcus Type III Synthetic Glycan-Conjugate Vaccine
  Chemistry (Weinheim an Der Bergstrasse, Germany). Jun, 2020  |   Pubmed ID: 32390224
• Chemoenzymatic Synthesis of 3-deoxy-3-fluoro-l-fucose and Its Enzymatic Incorporation into Glycoconjugates
  Chemical Communications (Cambridge, England). Jun, 2020  |   Pubmed ID: 32390019
• Synthesis and Structural Analysis of Aspergillus Fumigatus Galactosaminogalactans Featuring α-Galactose, α-Galactosamine and α-N-Acetyl Galactosamine Linkages
  Angewandte Chemie (International Ed. in English). Jul, 2020  |   Pubmed ID: 32342633
• Selective Synthesis of Galactooligosaccharides Containing β(1→3) Linkages with β-Galactosidase from (Saphera)
  Journal of Agricultural and Food Chemistry. Apr, 2020  |   Pubmed ID: 32279499
• Calorimetric Studies of Binary and Ternary Molecular Interactions Between Transthyretin, Aβ Peptides, and Small-Molecule Chaperones Toward an Alternative Strategy for Alzheimer's Disease Drug Discovery
  Journal of Medicinal Chemistry. Mar, 2020  |   Pubmed ID: 32124607
• Structure-Guided Design of a Group B Streptococcus Type III Synthetic Glycan-Conjugate Vaccine
  Chemistry (Weinheim an Der Bergstrasse, Germany). Jun, 2020  |   Pubmed ID: 32058627
• Glycans in Drug Discovery
  MedChemComm. Oct, 2019  |   Pubmed ID: 31814952
• Unraveling Sugar Binding Modes to DC-SIGN by Employing Fluorinated Carbohydrates
  Molecules (Basel, Switzerland). Jun, 2019  |   Pubmed ID: 31242623
• Optimization of Regioselective α-Glucosylation of Hesperetin Catalyzed by Cyclodextrin Glucanotransferase
  Molecules (Basel, Switzerland). Nov, 2018  |   Pubmed ID: 30400664
• Enzymatic Synthesis of a Novel Pterostilbene α-Glucoside by the Combination of Cyclodextrin Glucanotransferase and Amyloglucosidase
  Molecules (Basel, Switzerland). May, 2018  |   Pubmed ID: 29799509
• The Recognition of Glycans by Protein Receptors. Insights from NMR Spectroscopy
  Chemical Communications (Cambridge, England). May, 2018  |   Pubmed ID: 29662983
• Interactions Between a Heparin Trisaccharide Library and FGF-1 Analyzed by NMR Methods
  International Journal of Molecular Sciences. Jun, 2017  |   Pubmed ID: 28629128
• Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones)
  Molecules (Basel, Switzerland). Aug, 2016  |   Pubmed ID: 27527129
• Conformational Flexibility Around the Gal-β-(1 → 3)-Glc Linkage: Experimental Evidence for the Existence of the Anti-ψ Conformation in Aqueous Solution
  Carbohydrate Research. Oct, 2016  |   Pubmed ID: 27434833
• Detailed Investigation of the Immunodominant Role of O-Antigen Stoichiometric O-Acetylation As Revealed by Chemical Synthesis, Immunochemistry, Solution Conformation and STD-NMR Spectroscopy for Shigella Flexneri 3a
  Chemistry (Weinheim an Der Bergstrasse, Germany). Jul, 2016  |   Pubmed ID: 27376496
• Fluorinated Carbohydrates As Lectin Ligands: (19)F-Based Direct STD Monitoring for Detection of Anomeric Selectivity
  Biomolecules. Nov, 2015  |   Pubmed ID: 26580665
• Monitoring Glycan-Protein Interactions by NMR Spectroscopic Analysis: A Simple Chemical Tag That Mimics Natural CH-π Interactions
  Chemistry (Weinheim an Der Bergstrasse, Germany). Aug, 2015  |   Pubmed ID: 26177718
• Conformational Plasticity in Glycomimetics: Fluorocarbamethyl-L-idopyranosides Mimic the Intrinsic Dynamic Behaviour of Natural Idose Rings
  Chemistry (Weinheim an Der Bergstrasse, Germany). Jul, 2015  |   Pubmed ID: 26096911
• Recent Developments in Synthetic Carbohydrate-Based Diagnostics, Vaccines, and Therapeutics
  Chemistry (Weinheim an Der Bergstrasse, Germany). Jul, 2015  |   Pubmed ID: 26095198
• Glycans in Medicinal Chemistry: An Underexploited Resource
  ChemMedChem. Aug, 2015  |   Pubmed ID: 25974358
• Structure and Function of Prokaryotic UDP-Glucose Pyrophosphorylase, A Drug Target Candidate
  Current Medicinal Chemistry. 2015  |   Pubmed ID: 25620104