Lauren M. Sparks

Publications

• Sexual Dimorphism and the Multi-omic Response to Exercise Training in Rat Subcutaneous White Adipose Tissue
  Nature Metabolism. May, 2024  |   Pubmed ID: 38693320
• Muscle Mitochondrial Bioenergetic Capacities Are Associated with Multimorbidity Burden in Older Adults: the Study of Muscle, Mobility and Aging (SOMMA)
  The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Apr, 2024  |   Pubmed ID: 38605684
• Distinct Subpopulations of Human Subcutaneous Adipose Tissue Precursor Cells Revealed by Single-cell RNA Sequencing
  American Journal of Physiology. Cell Physiology. Apr, 2024  |   Pubmed ID: 38581663
• Percutaneous Biopsies of Skeletal Muscle and Adipose Tissue in Individuals Older Than 70: Methods and Outcomes in the Study of Muscle, Mobility and Aging (SOMMA)
  GeroScience. Jun, 2024  |   Pubmed ID: 38315316
• Understanding the Variation in Exercise Responses to Guide Personalized Physical Activity Prescriptions
  Cell Metabolism. Apr, 2024  |   Pubmed ID: 38262420
• Effects of Resveratrol on Circadian Clock Gene Expression in Young and Older Human Adipose-derived Progenitor Cells
  Aging. Jan, 2024  |   Pubmed ID: 38189848
• Translating In Vitro Models of Exercise in Human Muscle Cells: A Mitocentric View
  Exercise and Sport Sciences Reviews. Jan, 2024  |   Pubmed ID: 38126401
• Editorial: Exercise Intervention for Prevention and Management of Type 2 Diabetes
  Frontiers in Physiology. 2023  |   Pubmed ID: 37936578
• Comprehensive Interrogation of Human Skeletal Muscle Reveals a Dissociation Between Insulin Resistance and Mitochondrial Capacity
  American Journal of Physiology. Endocrinology and Metabolism. Oct, 2023  |   Pubmed ID: 37584609
• Leveraging Inter-individual Transcriptional Correlation Structure to Infer Discrete Signaling Mechanisms Across Metabolic Tissues
  BioRxiv : the Preprint Server for Biology. Oct, 2023  |   Pubmed ID: 37214953
• Schwann Cells Contribute to Demyelinating Diabetic Neuropathy and Nerve Terminal Structures in White Adipose Tissue
  IScience. Mar, 2023  |   Pubmed ID: 36895649
• Isolation of Nuclei from Frozen Human Subcutaneous Adipose Tissue for Full-length Single-nuclei Transcriptional Profiling
  STAR Protocols. Mar, 2023  |   Pubmed ID: 36853719
• The Mitochondrial Multi-omic Response to Exercise Training Across Tissues
  BioRxiv : the Preprint Server for Biology. Jan, 2023  |   Pubmed ID: 36711881
• Intermuscular Adipose Tissue in Metabolic Disease
  Nature Reviews. Endocrinology. May, 2023  |   Pubmed ID: 36564490
• Mitochondrial Energetics in Skeletal Muscle Are Associated With Leg Power and Cardiorespiratory Fitness in the Study of Muscle, Mobility and Aging
  The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Aug, 2023  |   Pubmed ID: 36462195
• Understanding Heterogeneity of Responses To, and Optimizing Clinical Efficacy Of, Exercise Training in Older Adults: NIH NIA Workshop Summary
  GeroScience. Feb, 2023  |   Pubmed ID: 36242693
• Single Cell Full-length Transcriptome of Human Subcutaneous Adipose Tissue Reveals Unique and Heterogeneous Cell Populations
  IScience. Aug, 2022  |   Pubmed ID: 35992069
• Aerobic Training Increases Mitochondrial Respiratory Capacity in Human Skeletal Muscle Stem Cells from Sedentary Individuals
  American Journal of Physiology. Cell Physiology. Aug, 2022  |   Pubmed ID: 35785986
• Skeletal Muscle Transcriptome Response to a Bout of Endurance Exercise in Physically Active and Sedentary Older Adults
  American Journal of Physiology. Endocrinology and Metabolism. Mar, 2022  |   Pubmed ID: 35068187
• The Metabolic Significance of Intermuscular Adipose Tissue: Is IMAT a Friend or a Foe to Metabolic Health?
  Diabetes. Nov, 2021  |   Pubmed ID: 34711670
• Twenty-four Hour Assessments of Substrate Oxidation Reveal Differences in Metabolic Flexibility in Type 2 Diabetes That Are Improved with Aerobic Training
  Diabetologia. Oct, 2021  |   Pubmed ID: 34402932
• A Metabolomic Signature of Glucagon Action in Healthy Individuals With Overweight/Obesity
  Journal of the Endocrine Society. Sep, 2021  |   Pubmed ID: 34337278
• Prolonged Glucagon Infusion Does Not Affect Energy Expenditure in Individuals with Overweight/Obesity: A Randomized Trial
  Obesity (Silver Spring, Md.). Jun, 2021  |   Pubmed ID: 34029448
• A Novel Endocrine Role for the BAT-Released Lipokine 12,13-diHOME to Mediate Cardiac Function
  Circulation. Jan, 2021  |   Pubmed ID: 33106031
• Individual Response Variation in the Effects of Weight Loss and Exercise on Insulin Sensitivity and Cardiometabolic Risk in Older Adults
  Frontiers in Endocrinology. 2020  |   Pubmed ID: 33013705
• An Improvement in Skeletal Muscle Mitochondrial Capacity with Short-term Aerobic Training is Associated with Changes in Tribbles 1 Expression
  Physiological Reports. Jun, 2020  |   Pubmed ID: 32562350
• Plasma Myokine Concentrations After Acute Exercise in Non-obese and Obese Sedentary Women
  Frontiers in Physiology. 2020  |   Pubmed ID: 32132925
• Adipose Tissue Quality in Aging: How Structural and Functional Aspects of Adipose Tissue Impact Skeletal Muscle Quality
  Nutrients. Oct, 2019  |   Pubmed ID: 31652734
• Endurance Training Remodels Skeletal Muscle Phospholipid Composition and Increases Intrinsic Mitochondrial Respiration in Men with Type 2 Diabetes
  Physiological Genomics. Nov, 2019  |   Pubmed ID: 31588872
• Targeting White Adipose Tissue with Exercise or Bariatric Surgery As Therapeutic Strategies in Obesity
  Biology. Mar, 2019  |   Pubmed ID: 30875990